铁蛋白检测在判断胸腹水积液性质中的应用

The value of PFt determination in the differentiation of exudate and transudate in pleural and abdominal cavity

目的了解黏蛋白、比密(SG)检测与铁蛋白(PFt)在判断胸腹水渗出液/漏出液中的关系及诊断价值。方法98例胸腹腔积液采用黏蛋白定性(即Rivalta试验)、SG与微粒子酶免分析法测定积液铁蛋白(PFt)水平,进行比对。结果用常规方法测定黏蛋白、SG,并以此判断出98例胸腹腔积液中渗出液为55例,漏出液为15例,不确定组为28例;积液铁蛋白(PFt)定量测定出渗出液组明显高于漏出液组(P<0.01)。其敏感度、特异度及准确度均高于常规方法。结论积液铁蛋白(PFt)检测有助于临床鉴别渗出液和漏出液,结合经典的Rivalta试验、SG测定同时检测积液铁蛋白(PFt)并进行综合判断积液的性质将对疾病的诊断、治疗和预后有重要作用。

Objective To investigate the value of muein, specific gravity （SG） and ferritin（PFt） in the differentiation of exudate and transudate in pleural and abdominal cavity. Methods Muein （ Rivalta test）, SG and PFt （ micro particle enzyme immunoassay） were determined in 98 hydrothorax and aseites samples. Results According to the measured values of muein and SG, 55 were exudate, 15 were transudate and 28 were uncertain. PFt levels were significantly higher in exudate than in transudate （ P 〈0. 01 ）. The sensitivity, specificity and accuracy of PFt in the differentiation of exudate and transudate were higher than those of routine method. Conclusions PFt measurement is helpful in distinguishing between exudate and transudate, but it is more useful in the diagnosis, treatment and prognostic evaluation if muein and SG are also measured.