气管插管后气囊上液与呼吸机相关性肺炎的病原学相关性分析

Etiological Analysis of Liquid on Air Sac Induce Ventilator-associated Pneumonia after Endotracheal Intubation

目的：探讨气管插管后气囊上液与呼吸机相关性肺炎（ventilator-associated pneumonia，VAP）的病原学相关关系。方法：我院2003年2月～2006年7月行呼吸机治疗者中127例发生VAP，均用气囊封闭气管，对每例气囊上液与下呼吸道分泌物采样行细菌培养，分析病原学结果。结果：气囊上液与下呼吸道分泌物病原菌株呈正相关，差异具有非常显著性意义（P〈0．01）。结论：气囊上液细菌感染是引发气管插管患者VAP的主要原因之一，在呼吸机辅助呼吸治疗中，重视清除气囊上液，可防止VAP的发生。

Objective ：To explore the relative etiologic relations of liquid on air sac induce ventilator-associated pneumonia after endotracheal intubation. Methods ：127 patients with VAP received endotracheal intubation or tracheotomy from February 2003 to July 2006. At the same time, liquid on air sac and secretion of lower respiratory tract of each patient was sampled and bacterium were cultured and etiologic resuhs of liquid on air sac and secretion of lower respiratory tract were compared. Results：There was positive correlation in results of liquid on air sac and etiologic strain of secretion of lower respiratory tract. Conclusion ： We should take suction and remove liquid on air sac in treatment and prophylaxis for ventilator-associated pneumonia.