生脉注射液治疗慢性阻塞性肺病急性加重期的临床疗效

Clinical observation of Shengmai injection in acute exacerbations of chronic obstructive pulmonary disease(COPD)

目的:探讨生脉注射液治疗慢性阻塞性肺病(COPD)急性加重期的临床疗效。方法:60例COPD患者随机分为两组,对照组(n=28)患者给予氧疗、抗炎、平喘、解痉、止咳化痰等常规治疗,试验组(n=32)在对照组治疗的基础上给予生脉注射液60mL+5%葡萄糖溶液(GS)或0.9%氯化钠溶液(NS)250mL中静脉滴注,qd,连用2周。结果:与对照组比较,治疗后试验组HR,RR,PaCO2均明显下降,白细胞、中性粒细胞明显降低,住院天数缩短,PaO2和SaO2明显上升。试验组与对照组总有效率分别为93·8%(30/32)和75·0%(21/28)(P<0·05)。结论:生脉注射液治疗COPD疗效确切。

Objective： To assess the efficacy of Shengmai injection in acute exacerbations of COPD. Methods： 60 patients with COPD were randomized into two groups. Control group （n = 28 ）received conventional treatment including oxygen therapy, anti-inflammation therapy, calming panting, spasmolysis, relieving cough and resolving phlegm. Test group （n = 32）was administered with Shengmai injection 60 mL plus 5% GS or NS 250 mL intravenously once daily for 2 weeks besides conventional treatment. Results： HR, RR, PaCO2 , WBC, neutrophil and hospitalized days of test group drop obviously while PaO2, SaO2 raised 75.0% （21/28） （P [ Key words] tions significantly. Total effective rates of test and control group were 93.8% （30/32） and 〈0.05） ,respectively. Conclusion ： Shengmai injection was effective for COPD.