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ADAm23基因的研究现状与展望 被引量:1

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摘要 恶性肿瘤的浸润与转移是有多种因素参与、多步骤、多阶段和多基因改变共同作用的结果,其中包括细胞-细胞间、细胞-基质间黏附性的改变。具有调节该功能的ADAm23基因由Sagane等于1998年在神经系统中首次克隆得出,随后的一系列研究证实了该基因的存在,并对其结构、功能、分布和表达情况都有了更深的认识。现就ADAm23基因的研究现状做一综述。
出处 《中华实验外科杂志》 CAS CSCD 北大核心 2007年第9期1151-1152,共2页 Chinese Journal of Experimental Surgery
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参考文献17

  • 1Primakoff P, Myles DG. The ADAM gene family:surface proteins with adhesion and protease activity. Trends Genet, 2000,16 : 83-87.
  • 2Sagane K,Ohya Y, Hasegawa Y, et al. Metalloproteinase-like, disintegrin-like, cysteine-rich proteins MDC2 and MDC3:novel human cellular disintegrins highly expressed in the brain. Biochem J, 1998, 334:93 -98.
  • 3Seals DF, Courtneidge SA. The ADAMs family of metalloproteases : multidomain proteins with multiple functions. Genes Dev, 2003,17:7-30.
  • 4Watabe-Uchida M, Masuda A, Shimada N, et al. Novel metalloprotease-disintegrin, meltrin epsilon ( ADAM35 ), expressed in epithelial tissues during chick embryogenesis. Dev Dyn ,2004,230:557-568.
  • 5Sun YP,Deng KJ,Wang F,et al. Two novel isoforms of Adam23 expressed in the developmental process of mouse and human brains. Gene,2004,325 : 171-178.
  • 6Yavari R, Adida C, Bray-Ward P, et al. Human metalloprotease-disintegrin Kuzbanian regulates sympathoadrenal cell fate in development and neoplasia. Hum Mol Genet, 1998,7 : 1161-1167.
  • 7Calmon MF,Colombo J,Carvalho F,et al. Methylation profile of genes CDKN2A ( p14 and p16), DAPK1, CDH1, and AD- Am23 in head and neck cancer. Cancer Genet Cytogenet ,2007,173:31-37.
  • 8Cal S, Frelje JM, Lopez JM, et al. ADAM 23/MDC3, a human disintegrln that promotes cell adhesion via interaction with the alphavbeta3 integrin through an RGD- independent mechanism. Mol Biol Cell, 2000,11 : 1457-1469.
  • 9Goldsmith AP, Gossage SJ, ffrench-Constant C. ADAm23 is a cell-surface glyco- protein expressed by central nervous system neurons. J Neurosci Res, 2004, 78: 647-658.
  • 10Costa FF, Colin C, Shinjo SM, et al. ADAm23 methylation and expression analysis in brain tumors. Neurosci Lett,2005,380 : 260-264.

二级参考文献15

  • 1陈剑英,张波,王国斌,郑海,陈庆勇,陈道达.人类乳腺癌基因表达分析[J].中华实验外科杂志,2005,22(4):429-431. 被引量:15
  • 2廖松林,现代诊断病理学手册,1995年,387页
  • 3Li J, Yen C, Parsons R, et al. PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer. Science, 1997, 275:1943-1947.
  • 4Liu H, Radisky DC, Wang F, et al. Polarity and proliferation are controlled by distinct signaling pathways downstream of PI3-kinase in breast epithelial tumor cells. J Cell Biol, 2004, 164: 603-612.
  • 5Lee JH, Miele ME, Hicks DJ, et al. KiSS-1, a novel human malignant melanoma metastasis-suppressor gene. J Natl Cancer Inst, 1996, 88:1731-1737.
  • 6West A, Volta PJ, Welch DR, et al. Chromosome localization and genomic structure of the KISS-1 metastasis suppressor gene (KISS1).Genomics, 1998, 54:145-148.
  • 7Lee JH, Welch DR. Identification of highly expressed genes in metastasis-suppressed chromosome 6/human malignant melanoma hybrid cells using subtractive hybridization and differential display. Int J Cancer,1997, 71 : 1035-1044.
  • 8Ohtaki T, Shintani Y, Honda S, et al. Metastasis suppressor gene KISS-1 encodes peptide ligand of a G-protein-coupled receptor. Nature,2001,411:613-617.
  • 9Lee DK, Nguyen T, O'Neill GP, et al. Discovery of a receptor related to the galanin receptors. FEBS Lett, 1999, 446 : 103-017.
  • 10Kotani M, Detheux M, Vandenbogaerde A, et al, The metastasis suppressor gene KISS-1 encodes KiSSpeptins, the natural ligands of the orphan G protein-coupled receptor GPR54. J Biol Chem, 2001, 276:34631-34636.

共引文献20

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  • 1Black RA, Rauch CT, Kozlosky C J, et al. A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cells. Nature, 1997,385:729-733.
  • 2Andreas G, Stefan H, Oliver M, et al. TACE cleavage of proamphiregulin regulates GPCR-induced proliferation and motility of cancer cells. EMBO J,2003,22:2411-2421.
  • 3Wu E, Croucher PI, McKie N, eta]. Expression of members of the novel membrane linked metalloproteinase family ADAM in cells derived from a range of haematological malignancies. Biochem Biophys Res Commun, 1997,235:437-442.
  • 4Zhang Q, Thomas SM, Lui VW, et al. Phosphorylation of TNF-α converting enzyme by gastrin-releasing peptide induces amphiregulin release and EGF receptor activation. Proe Natl Aead Sei USA,2006, 103 : 6901-6906.
  • 5McCullocb DR, Harvey M, Herington AC. The expression of the ADAMs proteases in prostate cancer cell lines and their regulation by dihydrotestosterone. Mol Cell Endocrinol,2000,167 : 11-21.
  • 6Kenny PA. TACE : a new target in epidermal growth factor receptor dependent tumors. Differentiation,2007,75:800-808.
  • 7Sternlicht MD, Sunnarborg SW. The ADAM17-amphiregulin-EGFR axis in mammary development and cancer. J Mammary Gland Biol Neoplasia,2008,13 : 181-194.
  • 8Sallmann FR, Bourassa S, Saint-Cyr J, et al. Characterization of antibodies specific for the caspase cleavage site on poly ( ADP-ribose ) polymerase:spccific detection of apoptotic fragments and mapping of the necrotic fragments of poly(ADP-ribose) polymerase. Biochem Cell Biol, 1997,75:451-456.
  • 9管洪庚,徐永峰,兰晶.血小板源生长因子通过PI3K/AKT途径促肝星状细胞增殖与Ⅰ型胶原合成[J].中华实验外科杂志,2007,24(11):1332-1334. 被引量:17

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