多形性胶质母细胞瘤的适形放疗新进展
Advances in 3-dimensional conformal radiotherapy for glioblastoma multiforme
摘要
多形性胶质母细胞瘤（glioblastoma multifornle，GBM）是最常见的脑胶质瘤之一，为高分级脑胶质瘤，放疗是其重要的治疗手段。Chang等研究表明，接受肿瘤局部放疗患者的中位生存时间（7个月）长于全脑放疗患者（5个月，P=0．020），而且毒副反应小，提高了患者生存质量。随着三维适形放疗（3-dimensional conformal radiotherapy，3D-CRT）的广泛应用，GBM放疗已经由原全脑放疗加局部肿瘤补量照射发展为肿瘤局部放疗。由于GBM具有浸润性生长、病程进展迅速的生物学特征，因此在临床工作中对其靶区的确定尚存在争议。现将GBM放疗的最新进展报告如下。
出处
《中华肿瘤杂志》
CAS
CSCD
北大核心
2007年第9期641-643,共3页
Chinese Journal of Oncology
关键词
多形性胶质母细胞瘤
适形放疗
Glioblastoma multiforme
Conformal radiotherapy
参考文献20
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