摘要
在整形与修复重建外科实践中,随意皮瓣是最为重要的技术之一,皮瓣成活率是直接反映皮瓣内血循环情况的标志。大量研究表明,皮瓣远端坏死的重要原因就是缺血/再灌注损伤。文章通过对大蒜素药理作用研究的分析,提出大蒜素通过清除氧自由基、抑制钙超载、抗炎及改善微循环变化等作用对缺血/再灌注损伤具有一定的保护作用。
In plastic and reconstructive surgery, random skin flap is one of the most widely used technology. The survival rate of the flap is the sign of the flap blood circulation. Many researches show that the ischemic reperfusion tissue injury is a crucial cause of the flap necrosis. The paper analyzes the action of the allitridium, which indicates that the allitridium has protective effects on the ischemic reperfusion tissue injury.
关键词
缺血
再灌注损伤
大蒜素
保护
ischemic reperfusion tissue injury
allitridium
protective effects
