摘要
对28例不同原因的成人肾病综合征患者血清抑制免疫复合物沉淀能力（ICPIC）和溶解免疫复合物能力（CMSIC）作了研究，发现所有患者均见ICPIC和CMSIC的异常下降，经激素治疗后，两者均见明显回升，但激素治疗敏感者的上升幅度明显高于激素治疗不敏感的难治性肾病患者，认为动态观察血清ICPIC和CMSIC可判断疾病活动度，早期预测疗效。同时认为患者血清补体功能下降与存在抑制因子有关。
The serum complernent mediated immune complex precipitation inhibition capacity (ICPIC) and immune complex solubilizing capacity (CMISC) in 28 adults with nephrotic syndrome were studied. The results showed tbat ICPIC and CMISC in aIl cases wer abnormally lower, but both were up sighficantly wth steriod hormone. Tne raised amplitude of ICPIC ana CMSIC was significantly higher in the patients who wer sensitive to steroid hormone than those with refracory nephrotic syndrome. Measuring ICPIC and CMISC in series could be used to assert the activity of the disease and predict the premature curative effect. The reduction of serum complement might be associated with the existence of immune inhibitory factor in serum.
