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特发性震颤的临床分析和多巴胺转运体功能显像 被引量：2

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摘要 特发性震颤（essential tremor，ET）是临床上最常见的神经科疾患之一。过去一直认为该病是一种良性病程、仅表现为震颤的遗传性疾病。但目前研究表明，ET表现出相当的异质性，可以呈进行性加重，对患者的生活质量造成严重的影响。不典型者与仅表现为震颤的早期帕金森病（Parkinson’s disease，PD）容易混淆，
作者 蒋雯巍 孙小丰 蒋雨平
机构地区 复旦大学附属华山医院老年科 复旦大学附属华山医院神经科
出处 《中华神经科杂志》 CAS CSCD 北大核心 2007年第9期618-619,共2页 Chinese Journal of Neurology
关键词 特发性震颤 临床分析 多巴胺转运体 功能显像 早期帕金森病 遗传性疾病 进行性加重 生活质量
分类号 R741 [医药卫生—神经病学与精神病学]
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参考文献10

  • 1Yahr MD, Orosz D, Purohit DP. Co-occurrence of essential tremor and Parkinson' s disease: clinical study of a large kindred with autopsy findings. Parkinsonism Relat Disord, 2003, 9:225-231.
  • 2邬剑军 蒋雨平.震颤[A].见:刘道宽 蒋雨平 江澄川等主编.锥体外系疾病[C].上海:上海科学技术出版社,2000.339,347.
  • 3Louis ED, Ford B, Wendt KJ, Lee H, et al. A comparison of different bedside tests for essential tremor. Mov Disord,1999, 14: 462-467.
  • 4王坚,蒋雨平,项景德,陈正平,管一晖,赵军,苏惠琳,郭丽萍,杨莉芹,邬剑军,丁正同.^(18)F-FP-β-CIT PET脑显像在早期诊断帕金森病中的意义[J].中华核医学杂志,2003,23(4):216-218. 被引量：24
  • 5Chaudhuri KR, Buxton-Thomas M, Dhawan V, et al. Long duration asymmetrical postural tremor is likely to predict development of Parkinson' s disease and not essential tremor: clinical follow up study of 13 cases. J Neurol Neurosurg Psychiatry ,2005, 76 : 115-117.
  • 6Koller WC, Busenbark K, Miner K. The relationship of essential tremor to other movement disorders: report on 678 patients. Essential Tremor Study Group. Ann Neurol, 1994,35:717-723.
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二级参考文献12

  • 1Kempster PA, Gibb WR, Stem GM, et al. Asymmetry of substantia nigra neuronal loss in Parkinson's disease and its relevance to the mechanism of levodopa related mootor fluctuations. J Neurol Neurosurg Psychiatry, 1989, 52:72-76.
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  • 6Fowler JS, Volkow ND, Wang GJ, et al. ^11C-cocaine: PET studies of cocaine pharmcokinetics, dopamine transporter availability and dopamine transporter occupancy. Nucl Med Biol, 2001, 28: 561-572.
  • 7Ma Y, Dhawan V, Mentis M, et al. Parametric mapping of ^18F-FPCIT binding in early stage Parkinson' s disesse: a PET study. Synapse,2002, 45: 125-133.
  • 8Rinne JO, Ruottinen H, Bergman J, et al. Usefulness of a dopamine transporter PET ligand ^18F-beta-CFT in assessing disability in Parkinson's disease. J Neurol Neurosurg Psychiatry, 1999, 67: 737-741.
  • 9Lee C,Samii A, Sossi V, et al. In vivo positron emission tomographic evidence for compensatory changes in presynaptic dopaminergic nerve terminals in Parkinson's disease. Ann Neurol, 2000, 47: 493-503.
  • 10Ouchi Y, Kanno T, Okada H, et al. Presynaptic and postsynaptic dopaminergic binding densities in the nigrostriatal and meaocortical systems in early Parkinson' s disease: a double-tracer positron emission tomography study. Ann Neurol, 1999, 46:723-731.

共引文献26

同被引文献29

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二级引证文献9

中华神经科杂志
2007年 第9期

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