Colorectal neoplasm:Magnetic resonance colonography with fat enema-initial clinical experience

AIM： To assess Magnetic resonance colonography with fat enema as a method for detection of colorectal neoplasm.METHODS： Consecutive twenty-two patients underwent MR colonography with fat enema before colonoscopy. Tl-weighted three-dimensional fast spoiled gradient- echo with inversion recovery sequence was acquired with the patient in the supine position before and 75 s after Gadopentetate Dimelumine administration. Where by, pre and post MR coronal images were obtained with a single breath hold for about 20 s to cover the entire colon. The quality of MR colonographs and patients＇ tolerance to fat contrast medium was investigated. Colorectal neoplasms identified by MR colonography were compared with those identified on colonoscopy and sensitivity of detecting the lesions was calculated accordingly.RESULTS： MR colonography with fat enema was well tolerated without sedation and analgesia. 120 out of 132 （90.9%） colonic segments were well distended and only 1 （0.8%） colonic segment was poor distension. After contrast enhancement scan, mean contrast-to-noise ratio （CNR） value between the normal colonic wall and lumen was 18.5 ± 2.9 while mean CNR value between colorectal neoplasm and lumen was 20.2± 3.1. By Magnetic resonance colonography, 26 of 35 neoplasms （sensitivity 74.3%） were detected. However, sensitivity of MRC was 95.5% （21 of 22） for neoplasm larger than 10 mm and 55.6% （5 of 9） for 5-10 mm neoplasm.CONCLUSION： MR colonography with fat enema and Tl-weighted three-dimensional fast spoiled gradientecho with inversion recovery sequence is feasible in detecting colorectal neoplasm larger than 10 mm.

瞄准：为颜色的察觉作为一个方法与胖灌肠估计磁性的回声 colonography 表面的瘤。方法：连续 22 个病人在结肠镜检查前与胖灌肠经历了先生 colonography。有倒置恢复顺序的 T1 加权的三维的快宠坏的坡度回响以前在背卧位与病人一起被获得并且在 Gadopentetate Dimelumine 管理以后的 75 s。在哪儿由， pre 和柱子先生花冠图象与单个呼吸抓住被获得让大约 20 s 盖住全部冒号。先生 colonographs 和病人的质量是到脂肪的忍耐造影剂被调查。先生 colonography 识别的 Colorectal 瘤与在结肠镜检查上识别的那些相比，检测损害的敏感因此是计算的。结果：没有镇静和痛觉缺失，有胖灌肠的先生 colonography 很好被容忍。120 (90.9%) 从 132，结肠的片断很好被扩张并且仅仅 1 (0.8%) 结肠的片断是差的扩张。在对比改进扫描以后，在正常的结肠的墙和腔之间的吝啬的 contrast-to-noise 比率(CNR ) 价值是 18.5 +/- 2.9 当吝啬的 CNR 在颜色之间珍视时，表面的瘤和腔是 20.2 +/- 3.1。由磁性的回声 colonography， 35 个瘤(敏感 74.3%) 中的 26 个被检测。然而， MRC 的敏感是 95.5%(22 中的 21 个) 为比 10 公里大的瘤并且 55.6%(9 中的 5 个) 为 5-10 公里瘤。结论：有胖灌肠的先生 colonography 和有倒置恢复顺序的 T1 加权的三维的快宠坏的坡度回响在检测颜色是可行的比 10 大的表面的瘤公里。