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DNA序列的特征数值及相似性分析 被引量：3

Novel Numerical Characterization and Analysis of Similarity of DNA Sequence
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摘要 利用2维图表示DNA序列,计算与该图对应的距离矩阵,求出距离矩阵的不变量—距离矩阵主对角线以外的次对角线之和的平均值,进而得到了DNA序列的一种特征数值,利用这种新的特征数值,对DNA序列进行相似性比较,得到了与现有的资料符合很好的结果. In this article, graphical representation of DNA prima ry sequences were generated. Distance matrices and the average values of the sum of elements in diagonal entries parallel to the main diagonal of distance matrices were calculated and used for the comparison of similarities among eight different DNA segments. The satisfactory results were a chived by this analysis.
作者 白凤兰
机构地区 大连交通大学理学院
出处 《数学的实践与认识》 CSCD 北大核心 2007年第18期95-99,共5页 Mathematics in Practice and Theory
关键词 DNA序列 图形表示 相似性 DNA sequence Graphical representation Similarity
分类号 Q523 [生物学—生物化学]
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参考文献16

  • 1Waterman M S. Introduction to Computational Biology: Maps, Sequences and Genomes[M]. Chapman & Hall, London, 1995.
  • 2Gates M A. A simple way to look at DNA[J]. J Theor Biol,1986,119(3): 319--328.
  • 3Randic M, Vracko M. On the similarity of DNA primary sequences[J]. J Chem Inf Comput Sci, 2000, 40(3): 599--606.
  • 4Randic M. On characterization of DNA primary sequences by a condensed matrix[J]. Chem Phy Letters,2000, 317(1--2) :29--34.
  • 5Randic M, Basak S C. Characterization of DNA primary sequences based on the average distance between bases[J]. J Chem Inf Comput Sci, 2001,41 (3) : 561--568.
  • 6Nandy A. graphical representation of DNA seqence[J]. J Chem Inf Comput Sci,2000,40(4):915--919.
  • 7Randic M, Vracko M, Lers N, Plavsic D. Nevel 2-D graphical representation of DNA seqences and their numerical characterization[J]. Chem Phy Letters, 2003,368 (1--2) : 1--6.
  • 8Randic M, Vracko M, Nandy A, Basak C. On 3-D graphical representation of DNA primary seqence and their numerical characterization[J]. J Chem Inf Comput Sci,2000,40(5) : 1235--1244.
  • 9Chunxin Yuan, Bo Liao, Tianming Wang. New 3D graphical representation of DNA seqence and their numerical characterization[J]. Chem Phy Letters, 2003,397 (5--6) : 412--417.
  • 10Randic M, Vracko M, Lers N, Plavsic D. Analysis of similarity/dissimilarty of DNA sequences based on novel 2-D graphical representation[J]. Chem Phy Letters, 2003,371 (1--2) : 202--207.

同被引文献15

引证文献3

二级引证文献14

数学的实践与认识
2007年 第18期

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