摘要
对２５例进展期胃肠道恶性肿瘤患者手术前后采用腹腔内热灌注化疗。灌注前后肝、肾功能正常。结果：患者白细胞、红细胞及血小板计数在灌注后第２￣３周下降明显，但第４周后开始回升。随访近２年，２例分别于术后６和９个月死亡，余２３例未发现肿瘤复发和转移。作者认为腹腔内化疗简单易行，毒副作用小，但在给药时间及药物剂量方面有必要进行前瞻性研究。
Pre-and postoperative perfusion of thermochemotherapy was used in 25 cases of advanced malignant tumors of digestive tract. There were no significant changes in hepatic and renal functions after perfusions. The erythrocyte, leukocyte and platelet counts reduced in the second and third week after the beginning of perfusion,but rose up in the 4th week. A 2-year follow-up revealed that 23 patients were still alive without recurrence or metastases except 2 cases died in the 6th and the 9th month after treatment. We claim that intraperitoneal thermochemotherapy is a simple and safe method. A prospective study is still necessary in deciding the dose and course.
