肠外营养对呼吸功能不全患者的影响

THE EFFECT OF PARENTERAL NUTRITION ON PATIENTS WITH RESPIRATORY DYSFUNC-TION

从加强医疗病房的重危患餐巾选取因呼吸衰竭而给予呼吸机支持的患者40例,随机分为A组20例进行肠外营养(parenteral nutrition,PN)治疗,B组20例未行PN治疗。对通气/换气功能各指标进行分析,结果两组患者的呼吸频率、pH、PaO_2、PaCO_2及HCO_3^-无明显差异;A组氧分压与吸入气氧浓度比值轻度降低,而肺泡-动脉氧压差及肺内分流明显升高。提示PN中的脂肪乳和高糖可能是导致呼吸功能改变的重要因素。

Forty critical patients with respiratory failure in the intensive care unit were randomly divided into two groups .Group A with administration of parenteral nutrition (PN) and Group B.no par-enteral nutrition given. Blood gas analysis and respiratory monitoring showed that the respiratory rate, pH,PaO2.PaCO2 and HCO3- had no marked difference between the two groups. But in Grouop A there was a slight decrease of PaO2/FiO2 and a marked increase of A-aDO2 and the pulmonary shunt. This study indicates that the content of fat emulsion and hydrocarbon in PN may be the main factor that affects the respiratory function.