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白血病抑制因子在妊娠大鼠植入期子宫中的表达 被引量：2

EXPRESSION OF LEUKEMIA INHIBITORY FACTOR IN UTERUS IN THE PROCESS OF EMBRYO IMPLANTATION IN RAT
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摘要 目的研究妊娠大鼠植入期子宫组织内白血病抑制因子(LIF)的表达。方法应用免疫组织化学超敏SP法对大鼠妊娠植入期子宫进行检测。结果发现LIF在子宫腔上皮细胞、腺上皮细胞、基质细胞、血管内皮细胞和肌细胞中均出现强阳性反应。结论LIF在胚泡植入过程中发挥着重要作用。 Objective To investigate implantation in rat uterus. Methods The im the expression of cytokine leukemia inhibitory factor（HF） in the process of embryo ultra sensitive SP method was used to detect the expression of UF protein in uterus. Results The expression of LIF was observed in uterine luminal epithelial cells, glandular epithelial cells, stromal cells, muscle cells and vascular endothelial cells; furthermore, immunoreactivity was stronger. Conclusion UF plays important roles in the process of implantation of earlier embryo.
作者 乔海莲 徐永平 张艳 赵瑾 曹力 范光丽
机构地区 西北农林科技大学动物科技学院
出处 《解剖学报》 CAS CSCD 北大核心 2007年第5期618-620,共3页 Acta Anatomica Sinica
基金 国家自然科学基金(39670550) 西北农林科技大学研究生科技创新基金(05ych020)资助项目
关键词 白血病抑制因子 子宫 免疫组织化学 大鼠 Leukemia inhibitory factor Uterus Immunohistochemistry Rat
分类号 S852.16 [农业科学—基础兽医学]
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参考文献11

  • 1Mitchell MH,Swanson RJ,Oehninger S.In vivo effect of leukemia inhibitory factor (LIF) and an anti-LIF polyclonal antibody on murine embryo and fetal development following exposure at the time of transcervical blastocyst transfer[J].Biol Reprod,2002,67 (2):460-464.
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二级参考文献23

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共引文献9

同被引文献18

  • 1彭晓琼,王志刚.超声与微泡在血管病变治疗方面的应用[J].声学技术,2004,23(F11):116-118. 被引量：5
  • 2张文杰,冯玉昆,王珏.白血病抑制因子在女性生殖系统的表达及调控[J].国外医学（妇幼保健分册）,2005,16(4):240-242. 被引量：2
  • 3Hanna A,Ariel R.Endometrial receptivity markers,the journey to successful embryo implantation. Human Reproduction Update,2006,12:731-746.
  • 4Tsai HD,Chang CC,Hsieh YY,et al.Leukemia inhibitory factor expression in different endometrial locations between fertile and infertile women throughout different menstrual phases.J Assist Reprod Genet,2000,17:415-418.
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  • 6Zhao M,Chang C,Liu Z,et al.Treatment with low-dose aspirin increased the level LIF and integrin β3 expression in mice during the implantation window.Placenta,2010,31:1101-1105.
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解剖学报
2007年 第5期

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