摘要
提出的MSA(Modified Spectral Alignment)算法,改进了SA(Spectral Alignment)算法中D(k)和k-最佳Spectral Alignment的求解方式,并在算法中引入"双端考虑"。实验结果数据表明,MSA算法有效地提高了鉴定含突变或翻译后修饰的蛋白质的能力。
The algorithm MSA is presented in this paper,which improved the way to compute D （k） and k-optimal Spectral Alignment of SA algorithm and took into account simultaneous analysis of N-terminal and C-terminal ions.The experiment result data shows that efficiently improves the capability of identifying proteins containing mutations or post-translational modifications.
出处
《计算机工程与应用》
CSCD
北大核心
2007年第28期61-64,共4页
Computer Engineering and Applications
关键词
蛋白质
翻译后修饰
突变
MSA算法
protein
Post-translational Modification
mutation
MSA algorithm
