精神分裂症患者脑部 CT 临床对照研究

A control study comparing CT brain between schizophrenic and neurotic patients

为探讨精神分裂症患者脑ＣＴ结果与临床的相关性，对１９９５年１月～１９９６年５月住院符合ＣＣＭＤ—２—Ｒ诊断标准的精神分裂症患者进行脑部ＣＴ检查，以同期门诊神经症患者的脑ＣＴ检查报告作对照，并与临床相关因素进行对照分析。结果发现精神分裂症组脑ＣＴ异常６９例（３２．４％），与对照组比较有极显著差异；前者病程＞５年，年龄４０岁以上，以阴性症状为主患者的脑萎缩发生率最高。

Objective:To compare CT brain between schizophrenic and neurotic patients.Method:213 schizophrenic patients(age 16￣49) had CT brain and were compared with findings of neurotic patients matched in age and sex.Diagnoses were made with CCMD-2-R.Results:There were 69(32 4%) schizophrenic patients and one(.47%)neurotic patients having cerebral atrophy with CT brain. The difference was highly significant. Cerebral atrophy was associated with negative symptoms,duration of illness longer than five years and age more than forty.Discussion:Chronic schizophrenic illness is associated with cerebral atrophy.