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急性大脑中动脉脑梗死动脉溶栓治疗临床分析 被引量:4

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摘要 目的评价超选择性动脉溶栓治疗急性大脑中动脉脑梗死的疗效和安全性。方法选择发病6h内的急性脑梗死患者51例,其中动脉溶栓组21例,接受脑血管造影证实为大脑中动脉急性闭塞并进行超选择性动脉溶栓治疗;常规治疗组30例,给予巴曲酶降纤治疗。观察两组NIHSS、Barthel指数(barthel index,BI),并进行疗效评定。结果动脉溶栓组21例患者中完全再通13例,部分再通5例,症状性颅内出血3例,死亡1例,术后90d优者(BI≥90)12例,良者(50≤BI<90)6例,差者(BI<50)1例,术后6个月生活状态优者15例,良者3例,差者1例。两组14d、90d的NIHSS评分,相比有统计学意义。结论动脉溶栓能够明显提高闭塞血管再通率,改善患者急性期临床症状和远期预后。
出处 《中国神经精神疾病杂志》 CAS CSCD 北大核心 2007年第9期554-556,共3页 Chinese Journal of Nervous and Mental Diseases
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参考文献9

  • 1John B,Peter S,Martins D,et al.Classfication and natural history of clinically identifiable subtypes of cerebral infarction.Lancet,1991,337(4):1521.
  • 2Sasaki O,Takeuchis,Koizumi T,et al.Complete recanalization via fibrinolytic therapy can reduce the number of ischemic territories that progress to infarction.AJNR,1996,17 (3):1661.
  • 3Kidwell CS,Saver JL,Carneado J,et al.Preditors of hemorrhagic transformation in patients receiving intra-arterial throonbolyis Sroke,2002,33(3):717.
  • 4Bourekas Ec,Slivka Ap,Shah R,et al.Intra-arterial thrombolyic therapy with 3 hours of the onset of stroke Neurosurgery,2004,54(1):39.
  • 5Endo S,Kuwayama N,Hirashima Y,et al.Results of urgent thrombolysis in patients with major stroke and atherothrombotic occlusion of the cervical internal carotid artery.AJNR,1998,19 (6):1169.
  • 6国家"九五"攻关课题协作组.急性脑梗死六小时以内的静脉溶栓治疗[J].中华神经科杂志,2002,35(4):210-213. 被引量:375
  • 7周俊山,姜建东.卒中的早期康复[J].国外医学(脑血管疾病分册),2004,12(5):358-360. 被引量:20
  • 8Kase CS,Furllan AT,Wechsler LR,et al.Cerebral hemorrhage after intra-arterial thrombolysis for ischemic stroke:the PROACT Ⅱ trial.Neurology 2001,57 (9):1603.
  • 9Gomez CR,Misra VK Morgan M,et al.Elective stenting of symptomatic middle cerebral artery stenosis.AJNR,2000,21 (5):971.

二级参考文献29

  • 1Asanuma H, Pavlides C, Neurobiological basis of motor learning in mammals. Neuroreport, 1997, 8:1 -4.
  • 2Howard SL, Krlshna C, Zimmerman RA Cranial MRI and CT. 4th ed.New York: NY, Mcgrcw-Hill, 1999. 517 -566.
  • 3Traversa R, Cicinelli P, Bassi A, et al. Mapping of motor cortical reorganization after stroke. Stroke, 1997, 28:110 - 117.
  • 4Wenk CA, Thallmair M, Kartje GL, et al. Increased corticofugal plasticity after unilateral cortical lesions combined with neutralization of the IN-1 antigen in adult rats. J Comp Neurol, 1999, 410:143 - 157.
  • 5Iwai M, Sato K, Omori N, et al. Three steps of neural stem cells development in gerbil dentate gyrus after transient ische-mia. J Cereb Blood Flow Metab, 2002, 22:411 -419.
  • 6Sato K, Hayashi T, Sasaki C, et al. Temporal and spatial differences of PSA-NCAM expression between young-adult and aged rats in normal and ischemic brains. Brain Res, 2001, 922:135 - 139.
  • 7Klintsova AY, Greenough WT. Synaptic plasticity in cortical systems.Curr Opin Neurobiol, 1999, 9:203 -208.
  • 8Johansson BB. Brain plasticity and stroke rehabilitation. The Willis Lecture. Stroke, 2000, 31:223 -230.
  • 9Watanabe H, Kumon Y, Ohta S, et al. Changes in protein synthesis and calcium honestasis in the thalamus of spontaneously hypertensive rat with focal cerebral ischemia. J Cereb blood Flow Metab, 1998, 18:686 -693.
  • 10Jones EG, Pons TP. Thalamic and brainstem contributions to large-scale plasticity of primate somatosensory cortex. Science, 1998, 282: 1121 -1125.

共引文献391

同被引文献50

  • 1练学淦,段传志,张媛,陈利锋,田时雨.动脉溶栓治疗急性大脑中动脉脑梗死(附16例报告)[J].中国神经精神疾病杂志,2005,31(5):344-346. 被引量:4
  • 2各类脑血管疾病诊断要点[J].中华神经科杂志,1996,29(6):379-380. 被引量:33022
  • 3穆雪梅.脑梗死出血性转化相关因素的分析[J].医学理论与实践,2006,19(11):1291-1292. 被引量:4
  • 4王艺东,刘生,黎祥喷,沈庆煜,李梅,闫振文,张泓,卢献平,黄如训.脑梗死患者的^99m Tc-HL91 SPECT乏氧显像[J].国际脑血管病杂志,2007,15(1):33-37. 被引量:8
  • 5Bayramoglu M, Karatas M, Leblebici B, et al. Hemorrhagic transformation in stroke patients [ J ]. Am J Phys Med Rehabil, 2003, 82(1) :48 -52.
  • 6Demchuk AM, Morgenstern LB, Krieger DW, et al. Serum glucose level and diabetes predict tissue plasminogen activator - related intracerebral hemorrhage in acute ischemic stroke [ J ]. Stroke, 1999,30( 1 ) :34 -39.
  • 7Vatankhah B, Dittmar MS, Fehm NP, et al. Thrombolysis for stroke in the elderly [ J ]. J Thromb Thrombolysis, 2005,20 ( 1 ) : 5 -10.
  • 8Berrouschot J, Rother J, Glahn J,et al. Outcome and severe hemorrhagic complications of intravenous thrombolysis with tissue plasminogen activator in very old ( > or = 80 years) stroke patients [ J ]. Stroke,2005,36 ( 11 ) :2421 - 2425.
  • 9Ribo M, Montaner J, Molina CA, et al. Admission fibrinolytic profile is associated with symptomatic hemorrhagic transformation in stroke patients treated with tissue plasminogen activator [ J ]. Stroke ,2004,35 ( 9 ) :2123 - 2127.
  • 10Trouillas P, Derex L, Philippeau F, et al. Early fibrinogen degradation coagulopathy is predictive of parenchymal hematomas in cerebral rt-PA thrombolysis: a study of 157 cases [ J]. Stroke, 2004,35 (6) : 1323 - 1328.

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