经静脉左心声学造影改善内膜分辨

Improvement of Endocardial Border Resolution by Left Ventricle Contrast Echocardiography Intravenously

对２１例肥胖患者应用自制的１％葡萄糖白蛋白声学造影剂（０．１４ｍｌ／ｋｇ）经外周静脉行左心声学造影。结果：左心腔显影≥２级的为２０例（９５．２％）；全部左室内膜节段的平均计分和３分内膜节段的百分比，由造影前的１．４５±１．０８和２４．５％增加到造影后的２．５４±０．８０和６９．１％；进而使观察者对９０．５％（１９／２１）的患者节段室壁运动的评价充满信心；所有患者未出现明显不良反应。表明该造影剂是一种安全有效的经静脉左心声学造影剂，静注后可改善内膜的分辨，增加对节段室壁运动评价的信心。

Sonicated 1% dextrose albumin of home make was administered intravenously (0 14ml/kg) in 21 selected fat patients during left ventricle(LV) contrast echocardiography.The results showed that the rate of LV chamber opacification(≥2 grade) was 95 2%。The mean grade and percentage of segments with optimal localization of LV′ endocadial borders significant increased from pre injection 1 45±1 08 and 24 5% to post injection 2 54±0 80 and 69 1%( P <0 01).And then in 19(90 5%) of the 21 patients,the investigator was confident about asseessing regional wall motion.No significant side effects occured.The data suggested this agent is a safe and effective contrast agent that,when administered intravenously,produces LV cavity opacification,improves endocardial border resolution and enhances observer′ confidence in assessing regional wall motion.