肝癌动脉化疗栓塞效果的病理评价

Histopathological study of hepatocellular carcinoma after transcatheter hepatic arterial chemo_embolization

目的研究肝细胞癌经动脉化疗栓塞治疗后癌肿的变化，探索提高疗效的方法．方法对动脉化疗栓塞治疗后行手术的３９例肝癌和１１例对照标本进行坏死程度与包膜、治疗次数、病理类型、分化、血管损伤及淋巴细胞浸润诸因素的相关性分析．结果完全坏死者６例，３０％～９５％坏死者１４例，仅５％坏死及无坏死者１９例，１１例ＤＳＡ无坏死．癌肿坏死程度与肿瘤分化、治疗次数、淋巴细胞浸润无关，而与病理类型、包膜、血管损伤有关．结论肝癌动脉化疗栓塞对于有包膜的中晚期肝细胞癌有明显效果．

AIM To study the histopathological changes after transcatheter arterial embolization (TAE) in hepatocellular carcinoma (HCC). METHODS Thirty_nine patients with HCC after TAE and 11 only after digital selective angiography (DSA) were analysed histopathologically, including pathological type, histological grade, necrotic degree, capsule, times of TAE therapy, injured vessel and lymphocyte infiltration.