小肠移植的内镜监测

Endoscopic monitoring of in small bowel transplantation

目的探讨内镜在小肠移植监测中的作用．方法动物实验，白色杂种猪行异体节段性小肠移植，移植小肠行ＴｈｉｒｙＶｅｌａ造口，由内镜通过肠造口观察应用（ｎ＝６）和未应用（ｎ＝６）免疫抑制剂移植小肠粘膜变化．临床研究，一女性短肠综合征患者接受异体全小肠移植，由内镜通过肠造口定时观察移植小肠．结果小肠移植排斥的内镜表现为局灶性肠粘膜红斑、糜烂和溃疡．弥漫性溃疡伴出血是排斥的晚期表现．结论内镜观察是小肠移植必需的监测手段．

AIM To investigate the role of endoscopic monitoring in small bowel transplantation. METHODS In experimental study white outbred pigs underwent segmental small intestine allotransplantation, proximal and distal intestine was brought out as stomas (Thiry Vella stoma), the grafts treated with ( n =6) or without ( n =6) immunosuppression were monitored by endoscopy via stomas. In clinical study, a female patient with short bowel syndrome received a total small intestine allotransplantation, and the graft was monitored by endoscopy via distal stoma.