幽门螺杆菌对功能性消化不良粘膜病变的影响

Effects of Helicobacter pylori on mucosal lesions in patients with functional dyspepsia

目的阐明幽门螺杆菌（Ｈｅｌｉｃｏｂａｃｔｅｒｐｙｌｏｒｉ，Ｈｐ）在功能性消化不良（ＦＤ）中的发病地位．方法对６７例Ｈｐ阳性和２９例Ｈｐ阴性ＦＤ患者胃窦部粘膜组织学病变（粘膜炎症、粘膜微血管损伤、粘膜萎缩和肠上皮化生）做对比分析．结果Ｈｐ阳性患者胃窦部粘膜组织学病变较Ｈｐ阴性者显著（Ｐ＜００５）．结论Ｈｐ对ＦＤ的发病具有重要作用，推想根治Ｈｐ可能会对Ｈｐ阳性的ＦＤ患者粘膜组织学病变的好转有益．

AIM To identify the role of Helicobacter pylori (Hp) in pathogenicity of functional dyspepsia (FD). METHODS Sixty seven Hp positive and 29 Hp negative patients were included in the study. Mucosal lesions (inflammatory infiltration, microvascular damage, mucosal atrophy and intestinal metaplasia) were compared between the two groups.