异体半月板库的建立及临床初步应用

Establishment of the allograft menisci bank and preliminary clinical application

[目的]建立同种异体半月板库,为半月板移植的临床应用研究打下基础。[方法]作者利用组织库供体来源的优势,结合低温冷冻技术保存半月板,初步建立了异体半月板库。临床进行半月板移植时,根据患者的需要和半月板库的记录资料合理选择,并注名有关操作规程。[结果]从2005～2006年底,作者已经建立了大约有300个不同大小半月板的半月板库,为临床提供了14个同种异体半月板。[结论]半月板库的建立为临床半月板移植的开展打下了基础;异体半月板移植手术的近期疗效是令人满意的,远期疗效尚需更进一步观察和更多病例的积累。

[ Objective] To investigate the establishment of the Allograft Menisci Bank so as to provide suitable allograft meniscus for clinical study of allograft meniscus transplantation. [ Method ] The allograft menisci from the plentiful donors of the tissue bank were achieved and preserved with the deep-frozen technique. Clinical use of allograft menisci should be based on practical requirement of patients and the data recorded in the Menisci Bank. [ Result] From 2005 to the end of 2006, an Allograft Menisci Bank was established which consisted with about 300 different-sized menisci and 14 allograft menisci were provided for clinical study. [ Conclusion ] Establishment of the Allograft Menisci Bank can provide a base for clinical meniscus transplantation. The short-term effects of the allograft menisci transplantation are satisfactory, but the long-term outcomes need more cases and further observation.