摘要
目的:研究中药敷脐治疗原发性痛经的临床效果以及对前列腺素(PgF_(2α)、PgE_2)表达的影响。方法:将205例患者随机分成两组,观察组104例,采用自制中药药膏外敷脐部治疗;对照组101例,采用硝苯地平治疗。结果:中药敷脐治疗后PgF_(2α)和PgE_2的浓度下降到正常范围,与对照组有统计学差异(P<0.01);中药敷脐治疗有效率为91.35%(95/104)明显优于硝苯地平44.55%(45/101)(P<0.01)。结论:中药敷脐治疗原发性痛经,疗效佳,无明显毒副作用,且用药经济,值得临床推广应用。
Objective: To study the treatment of primary dysmenorrheal and the expressive effect of prostaglandin by Chinese medicine plaster on navel . Method: Two hundred and five patients were divided into two groups randomly, the observation group 104 patients, treated by the self-made chinese medicinal externally applied on navel; the control group 101 patients, accepted the treatment of nifedipine. Result: After the treatment by Chinese medicine plaster on the navel, PgF2α and PgE2 decreased to the normal level. It had statistical difference to the control group (P 〈 0.01 ) ; the clinical effective rate of chinese medicine plaster group was 91.35% (95/ 104), and the nifedpine group was 44.55% (45/101) (P 〈 0.01 ). Conclusion: The treatment of primary dysmenorrheal by Chinese medicine plaster apply on the navel, receive a good curative effect, it has no poisonous side effect, and it is economical.
出处
《中国药师》
CAS
2007年第10期958-959,共2页
China Pharmacist
基金
深圳市盐田区科研基金(深盐科[2005]2号05W06)。
关键词
原发性痛经
中药敷脐
前列腺素
硝苯地平
Primary dysmenorrhea
Chinese medicine plaster on navel
Prostaglandin expression
Nifedipine