摘要
目的:建立咽炎片的含量测定方法。方法:采用高效液相色谱法。色谱柱:SHIMADZU VP-ODS(250 mm×4.6 mm,5μm).流动相:乙腈-水-冰醋酸(33:67:2),流速:0.8 ml·min^(-1),检测波长:274 nm,柱温:30℃。结果:丹皮酚在2.04～10.20μg范围内线性关系良好(r=0.999 9);平均加样回收率为99.67%,RSD=0.4%(n=5)。结论:该方法简便易行,结果准确可靠,可适用于咽炎片的质量控制。
Objective： To set up a method for quality control of Yanyan tablets. Method： Shimadzu VP-ODS column（250 mm × 4.6 mm,5 μm）was used. The mobile phase was acetonitrile-water-acetic acid （33： 67： 2）. The column temperature was 30 ℃, the wavelength for detection was 274 nm, flow rate was 0.8 ml·min^-1. Result： The linear range of paeonol was 2.04 - 10.20 μg. The paeonol average of recovery rate was 99.67%, and RSD was 0.4% （ n = 5 ）. Conclusion： The method is simple, accurate and suitable for the quality control of Yanyan tablets.
出处
《中国药师》
CAS
2007年第10期999-1001,共3页
China Pharmacist
