黑素瘤抑制性活性蛋白在恶性黑素瘤中的表达
被引量:1
摘要
黑素瘤抑制性活性蛋白(MIA)是近年来在研究黑素瘤细胞株HTZ19时分离的抑制黑素瘤细胞增殖的因子,其基因与在软骨细胞内发现的CD—RAP基因相同。在对转基因小鼠的研究中观察到,MIA主要在胚胎的软骨细胞内表达.在乳腺胚胎发育过程中也有该基因的短暂表达,乳腺发育成熟后即消失,并且发现MIA在部分乳腺癌及胰腺癌、胃癌中有一定表达。
出处
《中华皮肤科杂志》
CAS
CSCD
北大核心
2007年第10期644-645,共2页
Chinese Journal of Dermatology
基金
国家自然科学基金(30600535)
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