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强直性脊柱炎和未分化脊柱关节病患者血清转化生长因子β1水平及依那西普对其的影响 被引量:3

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摘要 强直性脊柱炎(As)与未分化脊柱关节病(USpA)是脊柱关节病(SpA)较常见的临床类型。转化生长因子β1(TGFβ1)在调节细胞生长、分化,促进细胞外基质堆积、骨重建、创伤修复等方面发挥重要作用,但TGFβ1在SpA的炎症、纤维化及骨化等发病过程中的作用目前尚不十分清楚。依那西普是重组人Ⅱ型TNFα受体一抗体融合蛋白,本研究通过检测依那西普治疗前后AS、USpA患者血清TGFβ1水平,探讨TGFβ1在AS、USpA发病中的意义。
出处 《中华内科杂志》 CAS CSCD 北大核心 2007年第10期852-853,共2页 Chinese Journal of Internal Medicine
基金 国家杰出青年科学基金(30325019) 国家自然科学基金(30571735) 广东省科技计划项目(2005A30801005)
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同被引文献51

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