2型糖尿病血糖控制与血脂水平的相互关系探讨

Relationship between blood glucose and lipidemia in patients with type 2 diabetes

目的探讨2型糖尿病存在的血脂异常,并观察血糖控制与血脂异常的关系。方法对90例2型糖尿病及30例正常对照组的空腹血脂、血糖结果进行分析统计,比较血糖控制良好组、控制较差组及对照组间血脂水平。结果与对照组相比,2型糖尿病患者甘油三酯(TG)、总胆固醇(TC)、低密度脂蛋白-胆固醇(LDL-C)、载脂蛋白B(apoB)水平明显升高,而高密度脂蛋白-胆固醇(HDL-C)水平降低。在2型糖尿病患者中,与血糖控制较差组相比,血糖控制良好组HDL-C明显升高,TG水平降低。结论血糖浓度可影响2型糖尿病患者的血脂水平,有效控制血糖,在一定程度上可改善2型糖尿病患者的血脂代谢。

Objective To investigate the lipidemia disorder in type 2 diabetes,and further explole the effect of blood gluose on lipidemia in patients with type 2 diabetes. Methods Blood glucose and lipids level were analyzed in 90 patients with type 2 diabetes and 30 heahhy control persons,lipids level were compared in patients with different fasting gluose lvevls. Result Higher level of triglyceride （ TG ）, cholesterol （ TC ）, low density lipoprotein cholesterol （ LDL - C ）, apolipoprotein B （ apoB ） and lower level high density lipoprotein cholesterol （ HDL - C） were found in type 2 diabetes group than controls. In type 2 diabetes,fasting glucose 〈 7.0 mmol/L group had higher HDL - C, lower TG level than fasting glucose 〉 7.0 mmol/L group. Conclusion Patients with type 2 diabetes have distinct disorder of blood lipid. High lipid may be improved with glucose in normal.