摘要
目的对虎杖根及根茎的化学成分进行研究。方法采用硅胶柱色谱进行分离,通过化学和波谱分析方法鉴定化合物结构。结果从其乙醇提取物的乙醚部分分离得到7个化合物,分别鉴定为大黄素甲醚(Ⅰ)、大黄素(Ⅱ)、黄葵内酯(Ⅲ)、β-谷甾醇(Ⅳ)、齐墩果酸(Ⅴ)、香豆素(Ⅵ)和2-乙氧基-8-乙酰基-1,4-萘醌(Ⅶ)。结论化合物Ⅶ为新化合物,命名为虎杖素A(cuspidatumin A),Ⅲ为首次从虎杖中分得。
Objective To study the chemical constitients of Polygonum cuspidatum. Methods The compounds were isolated through column chromatography and their structures were elucidated through physicochemical and spectral analyses. Results Seven compounds were obtained from the diethyl ether fraction of ethanol extract and identified as physcion （ Ⅰ）, emodin （ Ⅱ ）, ambrettolide （ Ⅲ）, β-sitosterol （ Ⅳ ）, oleanolie acid （ Ⅴ ）, coumarin （ Ⅵ ）, and 2-ethoxy-8-acetyl-1, 4-naphthoquinone （Ⅶ）. Conclusion Compound Ⅶ is a new compound named as cuspidatumin A, and compound Ⅲ is obtained from P. cuspidatum for the first time.
出处
《中草药》
CAS
CSCD
北大核心
2007年第10期1446-1448,共3页
Chinese Traditional and Herbal Drugs
基金
国家自然科学基金资助项目(30360119)
关键词
虎杖
虎杖素A
2-乙氧基-8-乙酰基-1
4-萘醌
黄葵内酯
the root and rhizome of Polygonum cuspidatum Sieb. et Zucc.
cuspidatumin A
2- ethoxy-8-acetyl-1, 4-naphthoquinone
mbrettolide
