期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

RNA干扰及其在医学中的应用 被引量：1

下载PDF
导出
作者 杨益超
机构地区 广西壮族自治区疾病预防控制中心
出处 《广西医学》 CAS 2007年第10期1546-1548,共3页 Guangxi Medical Journal
基金 广西科学研究与技术开发计划课题(桂科攻07190061)
关键词 RNA干扰 基因治疗
分类号 R394.8 [医药卫生—医学遗传学]
  • 相关文献

参考文献22

  • 1Guo S,Kemphues KJ.PAR-1,a gene required for establishing polarity in C.elegans embryos,encodes a putative ser/Thr kinase that is asymmetrically distributed[J].Cell,1995,81(4):611-620.
  • 2Fire A,Xu S,Montgomery MK,et al.Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans[J].Natrue,1998,391(6 669):806-811.
  • 3Yamamoto T,Omoto S,Mizuguchi M,et al.Double-stranded nef RNA interferes with human immuno deficiency virus type1 replication[J].Microbiol Immunol,2002,46(11):809-817.
  • 4Carthew RW.RNA interference:the fragile x syndrome connection[J].Curr Biol,2002,12(24):R852-R854.
  • 5Gan L,Anton KE,Masterson BA,et al.Specific interference with gene expression and gene function mediated by longds RNA in neural cells[J].J Neurosci Methods,2002,121(2):151-157.
  • 6Zamore PD,Tuschl T,Sharp PA,et al.RNAi:double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals[J].Cell,2000,101(1):25-33.
  • 7Hammond SM,Bernstein E,Beach D,et al.An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells[J].Nature,2000,404(6 775):293-296.
  • 8Bernstein E,Caudy AA,Hammond SM,et al.Role for a bidentate ribonuclease in the initiation step of RNA interference[J].Nature,2001,409(6 818):363-366.
  • 9Holen T,Amarzguioui M,Wiiger MT,et al.Positional effects of short interfering RNAs targeting the human coagulation trigger tissue factor[J].Nucleic Acids Res,2002,30(8):1757-1766.
  • 10Elbashir SM,Lendeckel W,Tuschl T.RNA interference is mediated by 21 and 22 nucleotide RNAs[J].Genes Dev,2001,15(2):188-200.

同被引文献19

  • 1吕明良,曾水清,肖青,夏又清.高糖联合低氧对体外培养的人视网膜色素上皮细胞HIF-1ɑ及VEGF表达的影响[J].华中科技大学学报（医学版）,2006,35(4):528-531. 被引量：4
  • 2吕明良,曾水清,肖青,李敏,夏辉.shRNA抑制人RPE细胞HIF-1α基因表达对VEGF及PEDF表达的影响[J].眼科研究,2007,25(9):688-691. 被引量：7
  • 3Gao G, Li Y, Zhang D, et al. Unbalanced expression of VEGF and PEDF in ischemia-induced retinal neovascularization [ J ]. FEBS Lett, 2001,489 ( 2 - 3 ) :270 - 276.
  • 4Semenza GL,Shimoda LA, Prabhakar NR. Regulation of gene expression by HIF-1 [J]. Novartis Found Syrup,2006,272:2 -8.
  • 5Boyd SR, Tan D, Bunce C, et al. Vascular endothelial growth factor is elevated in ocular fluids of eyes harbouring uveal melanoma:identification of apotential therapeutic window[ J ]. Br J Ophthalmol,2002, 86(4) :448 -452.
  • 6Young TA, Wang H, Munk S, et al. Vascular eudothelial growth factor expression and secretion by retinal pigment epithelial cells in high glucose and hypoxia is protein kinase C-dependent [ J ]. Exp Eye Res, 2005,80 ( 5 ) :651 - 662.
  • 7Dawson DW, Volpert OV, Gillis P, et al. Pigment epithelium-derived factor: a potent inhibitor of angiogenesis [ J ]. Science, 1999,285 (5 425) :245 -248.
  • 8Marciniak K, Butwicka A, Nowak JZ. PEDF :an endogenous factor displaying potent neuroprotective, neurotrophic ,and antiangiogenic activity[J]. Postepy Hig Med Dosw (Online),20136,60:387-396.
  • 9Tanimoto S, Kanamoto T, Mizukami M,et al. Pigment epithelium-derived factor promotes neurite outgrowth of retinal cells[ J ]. Hiroshima J Med Sci,2006,55(4) :109 - 116.
  • 10Notari L, Miller A, Martinez A,et al. Pigment epithelium-derived factor is a substrate for matrix metalloproteinase type 2 and type 9 : implications for downregulation in hypoxla [ J]. Invest Ophthalmol Vis Sci,2005,46(8) :2 736 - 2 747.

引证文献1

广西医学
2007年 第10期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部