杭州市184例反流性食管炎的临床特点及生存质量分析

Analysis of the clinical features and life quality of 184 patients with reflux esophagitis

目的通过症状量表和汉化版SF-36生存质量量表研究杭州市1年内经胃镜诊断的反流性食管炎(RE)患者的临床特点和生存质量状况。方法收集2004年9月至2005年9月杭州市七家省市级医院消化科门诊就诊的RE患者184例,记录患者的临床特点和生存质量状况,并进行相关因素的分析。结果REA级和B级的患者明显多于C级和D级患者。性别、吸烟、饮酒以及RE分级对症状评分无显著影响(P>0.05),年龄对症状评分有显著影响(P<0.05)。RE患者在SF-36各个维度的积分均有下降。吸烟、饮酒、年龄、性别以及内镜下分级对生存质量量表综合得分影响无显著性意义(P>0.05)。患病时间、症状量表评分对生存质量量表综合得分影响有显著性意义(P<0.05)。结论杭州市RE患者病情多较轻,年龄对RE症状的严重程度有显著影响,症状的严重程度和患病时间是影响患者生存质量的主要因素。

Objective To investigate clinical characteristics and life quality of reflux esophagitis （ RE ） in Hangzhou. Methods From Sep 2004 to Sep 2005,184 RE patients from 7 hospitals in Hangzhou were recruited to the study. We found out symptom characteristics and life quality of these patients through symptoms questionnaire and f Mos 36-item Short Form Health Survey. The relationship between age, sex, symptom and life quality was analyzed. Results The average score of symptoms questionnaire was 11.03. Gender, smoke, and drink had no distinct influence on symptom surv＇ey （P 〉 0. 05 ）. But age had distinct influence on symptom survey（ P 〈 0.05 ）. Each dimension of SF-36 decreased, especially body pain and role emotion. Gender, smoke,drink age and grade of gastroscopy had no distinct influence on SF-36, but the score of symptom questionnaire and SF-36 had distinctive correlation（ P 〈 0. 05 ）. Conclusion Age is the most important factor for the severity of symptom. The time of being sick and severity of symptom can influence quality of life of RE.