不同性别睡眠呼吸暂停综合征多导睡眠监测的研究

The research about polysomnography of sleep apnea syndromes in male and female patient

目的探讨睡眠呼吸暂停综合征(SAS)男女患者的临床特征及多导睡眠监测特点。方法根据整夜的多导睡眠图(PSG)监测结果将2004年1月至2006年6月于四川省第四人民医院睡眠呼吸疾患诊疗中心就诊的睡眠打鼾患者180例分为4组,即单纯鼾症组和轻、中、重度SAS组,对相关的临床特征及PSG监测指标进行比较。结果男性患者夜尿增多明显高于女性,差异有显著性意义(P<0.05或P<0.01),男性患者颈围明显大于同组女性(P<0.05或P<0.01)。中、重度SAS组女性患者低通气呼吸紊乱指数(HI)大于男性(P<0.05),中枢性睡眠呼吸紊乱指数(CAI)和混合性睡眠呼吸紊乱指数(MAI)明显低于同组男性(P<0.05);轻、中、重度SAS3组间血氧饱和度<90%时间(TSTSaO2<90%)男性患者数均大于女性,差异有显著性意义(P<0.05或P<0.01)。结论SAS男女患者具有不同的临床特点,在诊治过程中应考虑性别因素。

Objective To explore how different sex affect the clinical feature and apneic event,sleep time in patient with sleep apnea hypopnea syndrome. Methods According to the analysis of polysomnography （ PSG）, 133 male and 47 women with chief complain of snoring were divided into four groups simple snor,mild SAS,moderate SAS and severe SAS group. Compared related clinical feature and PSG data among them ,we found the difference in it. Results Male patient have more complication than female patient （P 〈 0. 05 or P 〈 0. 01 ） ,the neck size of male patient is bigger than female patient significantly（P 〈0.05 or P 〈0. 01 ）. The female patient HI is higher than male patient in moderate SAS and severe SAS group （ P 〈 0. 05 ）, but CAI and MAI is lower significantly （ P 〈 0. 05 ）. All of men TSTSaO2 〈 90% is bigger than women in all of three SAS group （P 〈 0. 05 or P 〈 0. 01 ）. Conclusion Our findings indicate that male and female patient with SAS show their own feature ,which could be helpful to clinical diagnosis and treatment.