不孕不育夫妇生殖道感染解脲支原体和沙眼衣原体的临床分析

THE ANALYSIS OF GENTIAL TRACT INFECTIONS OF UREAPLASMA UREALYTICUM AND CHLAMYDIA TRACHOMATIS IN THE STERILE COUPLES

目的:探讨不孕不育夫妇生殖道感染解脲支原体(UU)和沙眼衣原体(CT)的情况及夫妇间感染的相关性。方法:选择320对不孕不育夫妇为不孕不育组,108对已生育的健康夫妇为正常对照组分别进行生殖道UU和CT培养。结果:不孕不育组中丈夫UU阳性率为32.50%(104/320),CT阳性率为16.56%(53/320),UU、CT混合感染(UU+CT)阳性率为9.38%(30/320);对照组中丈夫UU阳性率为5.56%(6/108),CT阳性率为4.63%(5/108),UU+CT阳性率为2.78%(3/108),两组间比较差异均有统计学意义(均P<0.05)。不孕不育组中妻子UU阳性率为34.69%(111/320),CT阳性率为18.44%(59/320),UU+CT阳性率为12.19%(39/320);对照组中妻子UU阳性率为7.41%(8/108),CT阳性率为6.48%(7/108),UU+CT阳性率为1.85%(2/108),两组间比较差异均有统计学意义(均P<0.05)。不孕不育组夫妇间UU和CT感染均存在相关性(P<0.001)。结论:生殖道UU和CT感染是造成不孕不育的原因之一,对于不孕不育夫妇行病因学检查时均应常规行UU和CT检查。

Objective： The aim of this study is to explore gential tract infections of Ureaplasma Urealyticum and Chlamydia trachomatis in the sterile couples. Methods： We selected 320 sterile couples as the study group and 108 healthy couples as controles. All people were examined by UU,CT culture. Results.. The positive rate of UU,CT and UU＋CT was 32.50% （104/320）, 16.56 % （53/320） and 9.38% （30/320） in the group of sterile husbands respectively. And the positive rate was 5.56% （6/108）,4.63% （5/108） and 2.78% （3/108） in the group of healthy husbands respectively. There was significant difference between the two groups. The positive rate of UU,CT and UU ＋ CT was 33.69% （111/320）,18.44% （59/320）and 12.19% （39/320） in the group of sterile wives respectively. And the positive rate was 7.41% （8/108）, 6.48% （7/108） and 1.85% （2/108） in the group of healthy wives respectively. There was significant difference between the two groups. There was correlation between the husbands and wives in the sterile couples about gential tract infections of Ureaplasma Urealyti- cum and Chlamydia trachomatis. Conclusion： The infection of UU and CT is one of the major pathogenic factors of infertility. It is necessary to detect UU and CT when we look for the infertile factors.