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子宫内膜异位症中趋化性细胞因子ENA-78、IL-8的表达及意义 被引量:1

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摘要 目的:探讨趋化性细胞因子ENA-78、IL-8在子宫内膜异位症(EM)发生发展中的病理生理意义。方法:应用酶联免疫吸附法测定40例EM患者及38例非EM患者(对照组)腹腔液中ENA-78和IL-8水平。结果:EM组患者腹腔液ENA-78、IL-8的水平[(129.48±123.35)ng/L、(75.81±65.92)ng/L]均显著高于对照组[(50.19±18.31)ng/L、(30.58±19.94)ng/L,(P〈0.05)];EM组Ⅲ-Ⅳ期患者腹腔液中ENA-78、IL-8水平[(200.02±130.17)ng/L、(117.41±87.92)ng/L]均显著高于Ⅰ-Ⅱ期患者腹腔液ENA-78、IL-8水平[(51.46±12.42)ng/L、(48.02±19.11)ng/L,(P〈0.05)];EM组及对照组增生期和分泌期腹腔液中ENA-78、IL-8差异无统计学意义;腹腔液中ENA-78、IL-8的水平无明显相关性。结论:EM患者腹腔液中ENA-78、IL-8水平增高,且与期别相关,提示趋化性细胞因子在子宫内膜异位症的发生发展中有一定意义。
出处 《广西医科大学学报》 CAS 北大核心 2007年第4期570-571,共2页 Journal of Guangxi Medical University
基金 广西科学基金资助项目(No.桂科自0542082)
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