1Chun TW, Carryth L, Finzi D, et al. Quantification of latent tissue reservoirs and total body viral load in HIV-1 inIeetion [J ] .Nature, 1997,387:183- 188.
2Chun TW, Stuyver L, M izell SB, et al. Presence of a inducible HIV-1 latent reservoir during highly active antiretroviral therapy [ J ] .Proc Natl Acad Sci USA, 1997,94:13193 - 13197.
4Hemmi H,Takeeuehi O, Kawai T, et al. A Toll-like receptor recognizes bacterial DNA[ J ]. Nature,2000,408 : 740 - 745.
5Wagner H. Interactions between bacterial CpG-DNA and TLR9 bridge innate and adaptive immunity[ J ]. Curt Opin Microbiol,2002,5:62 -69.
6Ahmad-Nejad P, Hacker H, Rutz MP, et al.Bacterial CpG-DNA and lipoploysaccharides activate Toll-like receptors at distinct cellular compartments[J]. Eur J Immunol, 2002,32 : 1958 - 1968.
7Field AK.Oligonucleotides as inhibitors of human immunodeficieney virus[J ]. Curr Opin Mol Ther, 1999,1 : 323 - 331.
8Homer AA, Datta SK, Takabayashi K, et al. Immunostimulatory DNA-based vaccines elicit multifaceted immune responses against HIV at systemic and mucosal sites [ J ] .J Immunol, 2001, 167 ( 3 ) : 1584 - 1591.
9Schlaepfer E, Audige A, Beust BV, et al.CpG Oligodeoxynucleotides Block Human Immunodeficiency Virus Type 1 Replication in Human Lymphoid Tissue Intected Ex Vivo[ J ]. J Virol, 2004,78 (22) : 12344 - 12354.
10Beignon AS, McKenna K, Skobene M, et al.Endocytosis of HIV-1 activates plasmacytoid dendritic cells via Toll-like receptor-viral RNA interactions[ J ]. J Clin Invest, 2005,115(11) : 3265 - 3275.
