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血管平滑肌细胞增殖与STAT蛋白家族的关系 被引量:2

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摘要 酪氨酸蛋白激酶(JAK)/信号转导子和转录激活子(STAT)是近年来发现的细胞内信号转导途径,是一条细胞因子对免疫反应、血细胞生成、神经和胚胎发育调节及细胞增殖凋亡等多效性的传导通路。STAT蛋白是一种双功能信号分子,不仅能把细胞外信号传递到细胞内,而且直接参与细胞的基因调控。血管平滑肌细胞(VSMC)增殖是血管增殖性疾病发展的核心环节,也是目前防治的难点,因而有关病理学分子机制是血管增殖性疾病的研究热点。
出处 《中华实验外科杂志》 CAS CSCD 北大核心 2007年第10期1275-1276,共2页 Chinese Journal of Experimental Surgery
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参考文献19

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二级参考文献29

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