大承气汤对急性胰腺炎患者腹腔内压及腹腔隔室综合征发生率的影响

The Effect of Dachengqi Decoction on Intra-abdominal Pressure in Patients of Acute Pancreatitis

[目的]探讨大承气汤对急性胰腺炎患者腹腔内压的影响。[方法]60例患者随机分为两组,观察组给予常规治疗外加用大承气汤保留灌肠7d,对照组给予常规治疗加生理盐水灌肠。于入院当日及治疗期间检测两组患者膀胱内压(ICP)值以评价腹腔内压变化。参照文献制定腹腔隔室综合征(ACS)诊断标准,评估两组治疗期间ACS发生率。[结果]观察组ICP值于治疗期第4、5天时较对照组低;观察组治疗第3天ICP值开始下降,对照组第5天开始出现ICP值下降。两组ACS发生率无差异。[结论]大承气汤有降低急性胰腺炎患者腹腔内压的作用。

[Objective] To investigate the effect of Dachengqi Decoction on intra abdominal pressure（IAP） in patients of acute pan ereatitis（AP）. [Method] Sixty patients admitted for treatment on AP were stoehastie divided into two groups,30 patients were administered Daehengqi Deeoetion elysis for 2 hours everyday for 7 days; 30 patients with NS elysis and eonventional treatment. Test the intra-eystie pressure （ICP） of two groups patients during treatment period, evaluate the oeeurrenees of ACS of two groups. [Result] At the forth and fifth treatment day, the level of ICP in experimental group was lower than those in eontrol group; the level of ICP in experimental group descended from the third treatment day while in eontrol group whieh deseended from the fifth treatment day. The oeeurrenees of ACS of two groups were not different. [Conelusion] Daehengqi Deeoetion ean lower the level of IAP in patients of AP.