宁夏吴忠地区盐酸美沙酮维持治疗154例海洛因依赖者的疗效

Clinic effects of methadone maintenance treatment for 154 cases on heroin addicts in Wuzhong city of Ningxia

目的:探讨盐酸美沙酮替代海洛因维持治疗在宁夏地区实施的可行性、有效性。方法:采用问卷调查对受治者盐酸美沙酮维持治疗前后的效果进行评价。结果:宁夏吴忠地区吸食海洛因者人群结构复杂,吸食者平均时间达8.04年以上,多药物滥用增加了治疗依存性危险度。通过开展药物维持门诊试点工作,87.6%的受治者希望回归社会,维持正常人的生活质量;50%的受治者减轻了心理压力,改善了经济状况,能够参加身体其它疾病的治疗;57.1%的受治者与家庭成员关系发生极大改善;32.5%的受治者与家庭成员关系发生改善。结论:盐酸美沙酮维持治疗对海洛因依赖者治疗效果明显。由于该病属易反复发作的慢性脑疾病。需要多学科、多部门合作,给予受治者心理咨询及行为活动干预,才可保证治疗效果。

Objective： To evaluate the effectiveness and feasibility of using Methadone Hydrochloride as a substitution for heroin in the treatment of heroin addicts in Ningxia.Methods：The efficacy was evaluated by questionnaire for subjects before and after Methadone maintenance therapy（MMT）.Result： Heroin addicts in Wuzhong city have a complicated social relationship. The average time of drug-addicts is above 8.04 years. The risk of therapeutic compliance was increased by polydrug abusement. Through MMT in outpatient department.87.6% of the subjects want to return to society and live as a normal person; 50% have alleviated their mental stress and improved the economic condition so they could treat other diseases they have got.32.5% have improved the relationship with families.Conclusion： MMT has significant effect for heroin addicts, but as it is a high recurrent disease, we should cooperate among multi-discipline and multi-department, and use psychological counseling and behavior intervention which can ensure the efficacy.