慢性疲劳综合征中医病机转化的定量分析

Quantitative analysis on pathogenesis transformation of Traditional Chinese Medicine in chronic fatigue syndrome

目的对慢性疲劳综合征(CFS)中医病机转化进行定量分析。方法收集237例CFS患者,记录患者症状、舌象和脉象等临床资料,应用路径分析的方法,对患者中医病机转化进行分析。结果①脾虚病机可以影响阴液亏虚、精髓空虚和肾阳虚三种病机的发生;②精髓空虚可以影响阴液亏虚病机的发生;③阴液亏虚和肾阳虚两种病机之间可以互相影响。结论CFS的中医病机转换中,脾虚占有最重要的地位,并对其他病机的发生和转换形成关键影响。路径分析能够定量描述CFS中医病机转换关系。

Objective To analyze the pathogenesis transformation of Traditional Chinese Medicine （TCM） in chronic fatigue syndrome （CFS）. Method their symptoms, tongue demonstrations and pulses. Then patients＇ TCM pathogenesis transformation. Results We collected 237 CFS patients, and recorded we used path analysis method to analyze these ①Spleen deficiency could induce yin-fluid insufficiency, emptiness of essence-marrow, kidney yang deficiency. ②Emptiness of essence-marrow could induce yin-fluid insufficiency and kidney yang deficiency. ③Yin-fluid deficiency and kidney yang deficiency could influence each other. Conclusion In CFS TCM pathogenesis, spleen deficiency is at the most important position, and it can influence all the other four pathogenesis, in directly or indirectly ways. And, the path analysis method can quantitative descript the CFS patients＇ TCM pathogenesis transformation.