岩舒治疗原发性肝癌的临床观察

Yanshu Injection in the Treatment of Primary Hepatic Carcinoma:Observation of Clinical Efficacy

目的:观察复方苦参注射液(岩舒)治疗原发性肝癌的临床疗效。方法:选择无手术指征的中晚期肝癌患者30例,随机分为治疗组16例,对照组14例,观察近期疗效、生存质量(卡氏评分、临床症状改善积分)及不良反应变化。结果:治疗组患者肿瘤客观疗效对比,生存期对比分析,近期有效率,卡式评分增加与对照组比较差异均有显著意义。结论:复方苦参注射液有抗肿瘤、提高生存质量、减轻不良反应的作用。

OBJECTIVE： To study the effect of Compound Yanshu Injection （Yanshu）in the treatment on mid - late stage cancer. METHODS： Thirty patients with mid - late stage cancer were equally randomized into the comprehensive treatment group （n = 16） and the control group （n = 14）. The major outcome measures were short - term curative efficacy, quality of life （Kars score and clinical symptom imporvement score） and adverse drug reactions. RESULTS： After treatment, the objective curative efficacy, survival time, short - term effecte rate, increase of Kar＇ s score in group A was superior to those in group B, showing significant differences （ P 〈 0.05）. CONCLUSION ： Compound Yanshu Injection has anti - tumor effect and it is conducive to the enhancing of life quality and reduction of adverse reaction of chemotherapy in patients with mid - late stage cancer.