广西牛心包瓣膜临床应用的远期疗效—附13例随访报告

GUANGXI BOVINE PERICARDIAL VALVE CLINICAL APPLICATION AND RESULTS OF LONG-TERM

本文报告第一批广西牛心包瓣膜临床应用13例,对长期随访结果进行分析:13例中主动脉瓣置换术(AVR)3例,二尖瓣置换术10例。早期死亡率7.69%,晚期死亡率为4.2%病人年,5年生存率83.33%,牛心包瓣自然衰退,再手术率为1.0%病人年。经血液动力学测定,移植后牛心包瓣的跨瓣压力阶差:二尖瓣为0.133～0.267kPa,主动脉瓣为0.133kPa。二尖瓣有效面积为3.76～4.84cm^2,主动脉瓣口有效面积为2.26cm^2。资料表明,广西牛心包瓣膜的耐久性和血液动力学已达到国内,外先进水平。

This paper reported that 13 patients including aortic valve replacement(AVR)3 cases and mitral valve replacemment(MVR)10 cases,were performed with Guangxi bovine pericardial valve.The results of long-term follow-up showed that the hospital mortality rate was 7.69% (1/13),and the late mortality rate was 4.2% per patient year,actuarial 5 year survival rate was 83.33%(10/12),incidence of spontaneous degeneration and reoperation was 1% per patient year.Transvalvular gradient demonstrated that AVR was 0.133kPa and MVR 0.133～0.267kPa.The transvalvular effective area of AVR and MVR was 2.26 cm^2 and 3.76—4.84 cm^2 respectively.These results show that the hemodynamic performance and the durability of Guangxi bovine pericardial valve are up to the advanced world standard.