测定结肠粘膜菌群变化对大肠癌的早期诊断辅助性的研究

EARLY DIAGNOSIS OF CARCINOMA OF THE LARGE INTESTINE BY EXAMING THE INTESTINAL MUCOSA FLORA

测定结肠粘膜菌群变化对大肠癌的早期诊断辅助性的研究佳木斯医学院附属医院腔镜室佳木斯１５４００２孙玉清佳木斯医学院生理教研室吕密凯佳木斯医学院微生物教研室李丽秋马淑霞杨景云大肠癌是常见的恶性肿瘤之一，许多资料表明发病率逐年上升。病因及发病机理不清，有关...

Carcinoma of the large intestine is was of the common ones. The incidence of the disease had increased in recent years. The mechanism and the reason was still unknown. Some one reported that it maybe relative to the customs of diet and the materials like nitrite. Someone suggested that colonitis with polypus could become carcinoma easily. The reports of the relatives between the changes of intestinal flora and the carcinoma of the large intestine have not been seen. So we examined the colonic microflora of the four groups-carcinoma of long intestine,ulcer colonitis, colonic polypus and the normal controls. Enterobacter, enterococcus, bacteroides, Bifidobacterium and Lactobacillus was the dominant flora. The results of the flora were expressed by logarithm(Log/ml).It showed that Enterbacter, Bacteroide Entercoccus of the large intestine carcinoma group was more large than the other disease groups, and Bifidobacter and Lactobacillus decreased statistically(P<0 05).In the group of chronic colonitis with polypus, the same results could be found(P<0 001).So we recognized that it is benifit the early diagnosis and treatment of the large intestinal carcinoma to investigate the intestinal mucosa flora.