摘要
目的通过对收集到的药品不良反应/事件死亡病例报告的汇总分析,发挥药品不良反应监测工作的指导作用,以保障公众用药安全。方法采用回顾性研究方法,对江苏省2006年1月至2006年12月收集的33例药品不良反应事件死亡病例报告进行综合分析。结果死亡病例报告涉及老年人最多,涉及药物以抗微生物药最多见,药品不良反应累及的系统-器官以全身性损害最多见。结论抗微生物药应是监测的重点药品;预防和积极救治是防止药源性过敏性休克致死亡的主要措施,应加强对医药专业人员的教育与培训。
Objective To provide reference for clinic administration and ensure safety of drug use, collect and analyze of ADR/ADE death reports. Methods With retrospective case study, analyze 33 ADR/ADE death reports in Jiangsu province from 1, January, 2006 to 31, December , 2006. Results The case reports displayed that the aged people are the main part in the reports, and antibiotics is the chief. Most adverse reactions concerned general reactions.There also exhibited that the reports put in were not on time. Conclusion Antibiotics is the topic monitoring drug. Prophylaxis and remedying allergic shock are the major measure to prevent death, and it is significant that enhancing education and training to healthcare professionals.
出处
《中国药物警戒》
2007年第5期280-284,288,共6页
Chinese Journal of Pharmacovigilance
关键词
药品不良反应
死亡
报告
分析
adverse drug reaction（ADR）
death
report
analysis
