口服左氧氟沙星治疗化脓性扁桃体炎疗效分析

Efficacy of Orally Administered Levofloxacin in Treatment of Acute Suppurative Tonsillitis

目的 评价左氧氟沙星治疗急性化脓性扁桃体炎的有效性。方法 120例急性化脓性扁桃体炎的患者随机分成两组，试验组给予口服左氧氟沙星片剂500mg，1次／d；对照组静脉滴注青霉素钠，480万单位／次，2次／d，疗程7～14d。结果 共109例完成试验，试验组57例，临床有效率为92．98％，细菌清除率为87．81％；对照组52例，临床有效率为90．38％，细菌清除率为82．86％，试验组与对照组临床有效率及细菌清除率相比较差异均无统计学意义（P〉0．05）。结论 口服左氧氟沙星500mg能有效地治疗急性化脓性扁桃体炎。

OBJECTIVE To evaluate the efficacy of orally administered levofloxacin 500mg for the treatment of acute suppurative tonsillitis, METHOD6 Totally 120 proper patients were randomized into 2 groups and either group was in 1 ： 1 ratio. Patients in trial group received levofloxacin 500mg qd po. Patients in control group received benzylpenicillin sodium Ⅳ （4.8 million unit bid）. The course of treatment was 7 - 14 days. RESULTS From them 109 patients completed the study, 57 in trial group and 52 in control group. The results showed that in trial group levofloxacin could reach the total clinical efficacy of 92. 98% and the bacterium eradication rate of 87. 81% while in cotrol group it was 90. 38% and 82.86%. There was no statistic significant difference between the two groups in total clinical efficacy and bacterium eradication rate （P〉0. 05）. CONCLUSIONS Levofloxacin 500mg orally administered is effective in the treatment of acute suppurative tonsillitis,