摘要
目的了解嗜麦芽寡养单胞菌临床分布及耐药情况。方法细菌鉴定采用美国德灵公司Microscan Walkaway-40全自动细菌鉴定仪,PCIZ和NC11复合鉴定板进行体外药敏试验;数据处理应用WHONET5.3软件分析。结果自2005年1月-2006年9月临床送检标本中,共分离并鉴定嗜麦芽寡养单胞菌42株,选取常用的15种抗菌药物进行药物敏感试验结果显示,嗜麦芽寡养单胞菌对复方新诺明耐药率最低,为21.4%;其次为头孢哌酮/舒巴坦,耐药率为23.8%;对其他大多数抗菌药物也呈高度耐药;对亚胺培南和氨曲南耐药率为100.0%。结论嗜麦芽寡养单胞菌具有天然广谱耐药性,对该菌应加强监测与控制。
OBJECTIVE To investigate distribution and drug resistance status of Stenotrophomonas maltophilia. METHODS Microscan WalkAway-40 automatic analyzer from American Dade Company was used to identify bacteria. PCIZ and NCll combination plate was used to perform susceptibility test in vitro. The data were analyzed by WHONET5. 3 software. RESULTS The susceptibility to 15 antibiotics was tested in 42 clinic isolates of S. maltophilia from Jan 2005 to Sept 2006. The drug susceptibility test showed that SMZ-TMP had the lowest resistance rate(21. 4%). Then resistance rate of S. maltophilia to cefoperazone-sulbactam was 23.8%. And 100.0% isolates were resistant to imipenem and aztreonam. CONCLUSIONS S. maltophilia has natural broad- spectrum resistance. We should strengthen its monitoring and control.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2007年第10期1287-1288,共2页
Chinese Journal of Nosocomiology
关键词
嗜麦芽寡养单胞菌
医院感染
耐药性
Stenotrophomonas maltophilia
Nosocomial infections
Drug resistance