Ⅱa类细菌素的结构、生物合成与活性

Class Ⅱa Bacteriocins:Biosynthesis, Structure and Activity

乳酸菌产生的细菌素中Ⅱa类细菌素是很大的一类,这类细菌素数量众多且抑菌活性广,尤其是它们都对单核细胞增生李斯特氏菌有较强的抑菌活性,而且它们的理化性质也比较稳定,因而它们是最有希望作为食品添加剂应用的细菌素。对目前研究比较清楚的一些Ⅱa类细菌素的分子构成、基因组织、生物合成、作用方式进行了概述,并对未来Ⅱa类细菌素在食品中的应用途径做出了展望。

Class Ⅱ a bacteriocins can be considered as the major subgroup of bacteriocins from lactic acid bacteria, not only because of their large number, but also because of their activities and potential applications. They have first attracted particular attention as listericidal compounds and are now believed to be the next in line if more bacteriocins are to be approved in the future. The present review attempts to provide an insight into general knowledge available for class Ⅱ a bacteriocins and discuss common features and recent findings concerning these substances.