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非酒精性脂肪性肝病铁蛋白测定及意义 被引量：1

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摘要 入选NAFLD 90例和正常对照组(C)18例。采用稳态模式(HOMA)评价胰岛素抵抗,其中27例NAFLD和10例C应用校正CT测试管技术评价HFC。结果NAFLD组的腰臀比(WHR)、体重指数(BMI)、收缩压(SBP)、舒张压(DBP)、血糖(BG)(空腹+2小时)、胰岛素(Ins)(空腹+2小时)、胆固醇(TC)和甘油三酯(TG)高于C组(P<0.001)。NAFLD组的HFC、SF和丙氨酸氨基转移酶(ALT)水平高于正常对照组(P<0.05)。Logistic回归分析显示FBG、2hBG是脂肪肝形成主要的危险因素。结论:NAFLD患者SF水平显著升高,但是与脂肪肝不存在相关关系。
作者 盛励 刘军 查英 陈灶萍
机构地区 复旦大学附属上海市第五人民医院内分泌科
出处 《实用糖尿病杂志》 2007年第5期44-46,共3页 Journal of Practical Diabetology
关键词 非酒精性脂性肝脏疾病(NAFLD) 铁蛋白(SF) 肝脏脂肪含量(HFC)
分类号 R575.5 [医药卫生—消化系统]
  • 相关文献

参考文献9

  • 1刘军,高鑫,陈影,姚庆姑,陈刚,罗剑峰.非酒精性脂性肝脏疾病与胰岛素抵抗的关系[J].中华糖尿病杂志（1006-6187）,2004,12(2):114-119. 被引量：20
  • 2刘军,高鑫,陈刚,罗剑峰.CT定量评价脂肪肝[J].上海医学影像,2002,11(3):170-172. 被引量：12
  • 3Albano E, Motarane E, Vidali M, et al. Immune response to-wardards lipid peroxidation products a.s a predictor of progression of nonalcoholic fatty liver disease to advanced fibrosis. Gut 2005;54 (7) : 987 - 993.
  • 4黄聪武,白岚,崔生达,蔡俊杰.血清铁、铁蛋白和脂肪肝关系的研究[J].中华消化杂志,2003,23(4):211-212. 被引量：23
  • 5Brea A, Mosquera D, Martin E, et al.. Nonalcoholic Fatty Liver Disease Is Associated With Carotid Atherosclerosis: A Case - Control Study. Arteriosclerosis, Thrombosis, and Vascular Biology 2005 ; 25 (5) : 1045 - 1050.
  • 6Worwood M, Laboratory determination of iron status. In :Brock JH, Halliday JW, Pippard MJ, Powen LW, eds. Iron Metabolism in Health and Disease. London, UK:WB Saunders 1994:449 - 476.
  • 7李辉,王炳元.铁超负荷与脂肪肝[J].现代医药卫生,2004,20(8):630-631. 被引量：12
  • 8HAISO TJ, CHEN JC, WANG JD. Insulin resistance and ferritin as major determinants of nonalcoholic fatty liver disease apparently health obse patients. Int Obse Relat Metab Disord 2004;28:167 - 172.
  • 9杨冀衡,罗国辉,陆泽元,吴剑胜,胡雪松.血清铁蛋白与胰岛素抵抗的关系探讨[J].美国中华临床医学杂志,2005,7(3):221-223. 被引量：2

二级参考文献26

  • 1[1]Ricci C, Renata L, Eugenio G, et al. Noninvasive in vivo quatitative assessment of fat conent in human liver. Journal of Hepatology, 1997, 27:108- 113
  • 2[2]Cortez - Pinto H, Chatham J, Chacko CP, et al. Alterations in liver ATP homemostasis in human nonalcoholic steatohepatitis: a pilot study. JAMA, 1999, 282:1659-1664
  • 3[3]Sheth SG, Gordon FD, Chopra S. Nonalcoholic steatohepatitis.Ann Intern Med, 1997, 126:137- 145
  • 4[4]Sharabi Y, Eldad A. Nonalcoholic fatty liver disease is associated with hyperlipidemia and obesity. Am J Med, 2000, 109:171 - 176
  • 5[5]Piekarski J, Moss, A. Difference between liver and spleen CT numbers in the normal adult: its usefulness in predicting the presence of diffuse liver disease. Radiology, 1980, 137:727 - 729
  • 6[6]Graif M, Yanuka M, Baraz M, et al. Quantitative estimation of attenuation in ultrasound video images: correlation with histology in diffuse liver disease. Invest Radiol, 2000, 35:319 - 324
  • 7[7]Taniguchi N. Estimation of hepatorenal echo contrast by echo - intensity histogram and its problem. Ultrasonics, 1991, 18:856 - 904
  • 8Rouach H, Fataccioli V, Gentil M, et al. Effect of chronic ethanol feeding on lipid peroxidation and protein oxidation in relation to liver pathology. Hepatology, 1997, 25:351-355.
  • 9George DK, Goldwurm S, Mac Donald GA, et al. Increased hepatic iron concentration in nonalcoholic steatohepatitis is associated with increased fibrosis. Gastroenterology, 1998, 114:311-318.
  • 10Graudal N, Milman N, Galloe AM, et al. Distribution of liver haemosiderin iron in 187 patients with various types of hepatic deseases. APMIS, 1996, 104:220-226.

共引文献60

同被引文献15

  • 1吴海娅,贾伟平,魏丽,陆俊茜,包玉倩,项坤三.肥胖及2型糖尿病患者血清视黄醇结合蛋白4水平的变化及其临床意义[J].中华内分泌代谢杂志,2006,22(3):290-293. 被引量：95
  • 2Yang Q, Graham TE, Mody N, et al. Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes[J]. Nature, 2005,436(7049) : 356-362.
  • 3Ross AC. Overview of retinoid metabolism[J]. J Nutr, 1993, 123(2 Suppl) :346-350.
  • 4Lalor PF,Faint J,Aarbodem Y,et al. The role of cytokines and chemokines in the development of steatohepatitis[J]. Semin Liver Dis,2007,27(2) : 173-193.
  • 5Roskams T, Yang SQ, Koteish A, et al. Oxidative stress and oval cell accumulation in mice and humans with alcoholic and nonalcoholic fatty liver disease[J]. Am J Pathol, 2003,163 (4) 1301-1311.
  • 6Graham TE,Yang Q,Bluher M,et al. Retinol-binding protein 4 and insulin resistance in lean,obese,and diabetic subjects[J]. N Engl J Med, 2006,354(24) : 2552-2563.
  • 7Seo JA,Kim NH,Park SY, et al. Serum retinol-binding protein 4 levels are elevated in non-alcoholic fatty liver disease[J]. Clinical Endocrinology, Z008,68(4) : 555-560.
  • 8Wu H,Jia W,Bao Y,et al. Serum retinol binding protein 4 and nonalcoholic fatty liver disease in patients with type 2 diabetes mellitus[J]. Diabetes Res Clin Praet,2008,79(2) :185-190.
  • 9Wrede CE, Buettner R, Bollheimer LC, et al. Association between serum/erritin and the insulin resistance syndrome in a representative population[J]. Eur J Endocrinol, 2006,154 (2) : 333-340.
  • 10Fernandez-Real JM, Moreno JM, Ricart W. Circulating retinol- binding protein-4 concentration might re[lect isulin rsistanee- associated iron overload[J]. Diabetes, 2008,57 (7) : 1918-1925.

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实用糖尿病杂志
2007年 第5期

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