摘要
目的探讨家栖鼠对抗凝血灭鼠剂的抗药性变化。方法按全国鼠类抗药性监测协作组统一方法,进行无选择性摄毒试验。结果经对江门市城区(蓬江、江海、新会区)内所捕获的129只褐家鼠、37只黄胸鼠、15只小家鼠进行抗药性监测,其抗性率分别为0、10.81%和46.67%,总平均摄药剂量分别为12.00、143.12和582.41 mg/kg,按家栖鼠抗药性检验标准,小家鼠对第一代抗凝血剂杀鼠灵已形成抗药性种群,黄胸鼠有抗药性个体产生。结论以小家鼠为优势种的场所,要考虑使用第二代抗凝血灭鼠剂;而以褐家鼠、黄胸鼠为主的场所,则可继续使用第一代抗凝血灭鼠剂,但应加强对灭鼠药物的敏感性监测,科学、合理用药。
Objective To study the resistant development of anticoagulant rodenticide in commensal rodents. Methods Unselective feeding method was used, which was established by "Rodenticide-resistance Monitoring Cooperation Group in China" in 1985. Results The rodents (129 Rattus norvegicus, 37 R.flavipectus and 15 Mus musculus) caught in Jiangmen' three city zone (Pengjiang, Jianghai, Xinhui) of Jiangmen city were tested. The resistance rate differs from 0, 10.81% and 46.67 % for R. norvegicus, R. flavipectus and M. musculus with average taken dosages 12.00, 143.12 and 582.41 mg/kg respectively. The result shows that M. musculus have developed resistance to anticoagulant rodenticide Ⅰ and R.flavipectus has individual resistance. Conclusion The rodenticide Ⅱ should be used in the areas of M. musculus. The anticoagulant rodenticide Ⅰ can be still used but should be used scientifically and properly with careful tests of sensitivity.
出处
《中国媒介生物学及控制杂志》
CAS
CSCD
北大核心
2007年第5期360-362,共3页
Chinese Journal of Vector Biology and Control
基金
广东省医学科学技术研究基金(A2005092)
广东省江门市科研项目(江科[2006]70号)
关键词
家栖鼠
抗凝血灭鼠剂
杀鼠灵
抗药性
监测
Commensal rodent
Anticoagulant rodenticide
Warfarin
Resistance
Monitor