广州市2006年登革热疫情流行病学特征分析

Analysis on characteristics of dengue fever epidemic in Guangzhou,2006

目的分析广州市2006年登革热疫情流行病学特征,为登革热预防控制工作的开展提供参考依据。方法对广州市疫情监测与报告信息系统和实验室监测信息系统,以及相关的现场调查报告、疫情简报等进行统计与分析。结果广州市2006年报告登革热输入性病例10例,本地感染病例765例,累计发病率为10.19/10万,无死亡病例,疫情涉及9个区82个行政街(镇);全年本地疫情流行期为6月中旬至12月上旬,明显存在8-9月和10-11月两次发病高峰;共发生60起暴发疫情,其中10起暴发疫情对流行曲线的走势有较大影响,累计病例456例,占全年全市总报告病例数的59.61%;实验室监测表明2006年广州市病毒流行株为Ⅰ型登革病毒,各1例输入性病例,毒株分别为Ⅲ、Ⅰ型登革病毒。结论2006年广州市发生登革热流行,其持续时间长,波及范围较广;疫情由输入性病例引起本地暴发流行的可能性较大,尚无明确证据表明登革热在广州市已形成地方性流行的态势。

Objective To analyze characteristics of the dengue fever epidemic and thereby provide references for future prevention and control. Methods Data from infectious disease surveillance and reporting system and laboratory recording surveillance system, as well as field investigation report and epidemic briefings were reviewed and analyzed. Results There reported accumulatively 10 imported cases, which almost come from south-east Asia, and 765 native cases of dengue fever in 2006 in Guangzhou. The accumulative incidence was 10.19 per 100 000 and no death was reported. The epidemic spread nine districts and eighty-two administrative streets and spanned from mid-June to early Dec. Two obvious peaks, one from August to September and another from October to November, were observed. 10 of total 60 outbreaks influenced epidemic curve trends, which included 456 cases, i.e. 59.61% of total reported cases. The findings from lab surveillance indicated that the epidemic was caused by type I dengue fever virus but also found one type III strain from imported case. Conclusion The Dengue fever epidemic of Guangzhou in 2006 which had a long prevalent period and many spreading areas, observed a plausibility of causation with imported cases from neighboring countries and no definite evidence indicated it would become endemic prevalence in Guangzhou.