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中枢神经系统发育的不对称细胞分裂机制 被引量：1

Mechanisms of asymmetric cell divisions in CNS development
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摘要 无论在无脊椎动物还是脊椎动物中,组成中枢神经系统(CNS)的大多数细胞都是由极性神经祖细胞不对称分裂而来。通过简要综述果蝇(Drosophila melanogaste)成神经母细胞(NB)不对称分裂机制,并与近年来在脊椎动物不对称细胞分裂上取得的研究成果相比较,尝试找出两个系统的相似性和相异性。 Most cells that constitute the central nervous system（CNS） are generated from asymmetric divisions of polarized neural progenitors in both invertebrate and vertebrate. This paper briefly reviewed the mechanism of asymmetric cell division in Drosophila melanogaste neuroblasts（NB） and compared it with asymmetric cell divisions in vertebrate based on recent progresses made in this field, trying to find out the similarities and differences between both systems.
作者 边文杰 陈晓萍
机构地区 浙江工业大学生物与环境工程学院
出处 《生物学杂志》 CAS CSCD 2007年第5期5-7,24,共4页 Journal of Biology
基金 国家人事部留学择优基金 浙江省教育厅基金资助项目(项目号:20040586)
关键词 不对称细胞分裂 命运决定因子 果蝇 中枢神经系统 asymmetric cell division fate determinant Drosophila central nervous system
分类号 Q426 [生物学—神经生物学]
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参考文献17

  • 1Betschingert J,Knoblich J A.Dare to be different:asymmetric cell division in Drosophila,C.elegans and vertebrates[J].Curr Biol,2004,14(16):R674-R685.
  • 2Wodarz A,Huttner W B.Asymmetric cell division during neurogenesis in Drosophila and vertebrates[J].Mech Dev,2003,120(11):1297-1309.
  • 3Hutterer A,Betschinger J,Petronczki M,et al.Sequential roles of Cdc42,Par-6,aPKC,and Lgl in the establishment of epithelial polarity during Drosophila embryogenesis[J].Dev Cell,2004,6(6):845-854.
  • 4Roegiers F,Jan Y N.Asymmetric cell division[J].Curr Opin Cell Biol,2004,16(2):195-205.
  • 5Betschinger J,Mechtler K,Knoblich J A.Asymmetric segregation of the tumor suppressor brat regulates self-renewal in Drosophila neural stem cells[J].Cell,2006,124(6):1241-1253.
  • 6Wodarz A.Molecular control of cell polarity and asymmetric cell division in Drosophila neuroblasts[J].Curr Opin Cell Biol,2005,17(5):475-481.
  • 7Bhalerao S,Berdnik D,Torok T,Knoblich A J.Localization-dependent and-independent roles of Numb contribute to cell-fate specification in Drosophila[J].Curr Biol,2005,15(17):1583-1590.
  • 8Wang H,Chia W.Drosophila neural progenitor polarity and asymmetric division[J].Biol Cell,2005,97(1):63-74.
  • 9Kaltschmidt J A,Davidson C M,Brown N H.et al.Rotation and asymmetry of the mitotic spindle direct asymmetric cell division in the developing central nervous system[J].Nat Cell Biol,2000,2(1):7-12.
  • 10Siegrist S E,Doe C Q.Microtubule-induced Pins/G α i cortical polarity in Drosophila neuroblasts[J].Cell,2005,123(7):1323-1335.

同被引文献37

  • 1Betschingert J et al. Curr Biol, 2004, 14:R674.
  • 2Siegrist SEet al. Development, 2006, 133:529.
  • 3Noctor SC et al. Nat Neurosci, 2004, 7:136.
  • 4Gotz Met al. Nat Rev Mol Cell Biol, 2005, 6:777.
  • 5Wodarz A. Curr Opin Cell Biol, 2005, 17:475.
  • 6Huttner WB et al. Curr Opin Cell Biol, 2005, 17:648.
  • 7Siegrist SEet al. Genes Dev, 2007, 21:483.
  • 8Knoblich JA. Cell, 2008, 132:583.
  • 9Rebollo E et al. Dev Cell, 2007, 12:467.
  • 10Yamashita YM et al. J Cell Biol, 2008, 180:261.

引证文献1

生物学杂志
2007年 第5期

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