气相色谱法测定盐酸普鲁卡因注射液的含量

Determination of Procaine hydrochloride injection by GC

目的采用气相色谱法(GC)测定盐酸普鲁卡因注射液的含量。方法采用J&W DB-1毛细管柱(30 m×0.452mm,2.55μm),载气为氮气,柱温220℃,检测器FID温度250℃。结果平均回收率为99.0%,RSD=0.84%(n=5)结论所建方法简便,结果准确,可用于盐酸普鲁卡因注射液的质量控制。

OBJECTIVE To establish a method for determination of procaine hydrochloride in Procaine hydrochloricle injection by GC. METHODS With gas chromatography, J＆W DB - 1 capillary chromatographic column （ 30 m × 0. 452 mm, 2.55 μm） was used. Carrier gas was nitrogen. The column temperature was 220℃, the detector FID temperature was 250℃. RESULTS The average recovery was 99.0% with RSD of 0. 84% （n = 5 ）. CONCLUSION The method is simple and accurate. It could be applied for the quality control of Procaine hydrochloride injection.