^(14)C尿素呼气试验检测幽门螺杆菌临床应用价值的研究

Study on the clinical value of ^(14)C urea breath test in the detection of HP

目的:探讨14C尿素呼气试验(14C-UBT)的临床应用价值。方法:126例患者经过胃镜证实胃十二指肠溃疡56例、浅表性胃炎70例,应用14C-UBT、尿素酶试验(RUT)、组织切片法(Warthin-Starry银染色法)三种方法检测,是否有幽门螺杆菌(HP)的感染。结果:14C-UBT、RUT和组织切片三种方法的HP阳性率分别为83.16%、73.12%、69.15%,以14C-UBT法HP阳性检测率最高,三种方法统计学上无差异。结论:14C-UBT与目前常用HP检测方法具有类似的检出率,但它简便、快速、安全,值得临床推广应用。

Objectlve：To study the clinical value of ^14C urea breath test（^14C-UBT） in the detection of helicobacter pylori（HP）.Methods：The three kinds of examination methods which were ^14C-UBT,urease test（RUT） and histological section（Warthin-Starry silver staining） were used simultaneously to detect whether there was HP infection in 126 patients including 56 confirmed as gastroduodenal ulcer by gastroscope and 70 superficial gastritis.Results：The positive rates of ^14C-UBT,RUT and histological section were 83.16% ,73.12% and 69.15% respectively.2The positive rate of ^14C-UBT seemed to be the highest,but no statistical difference among that in three methods. Conclusion： ^14C-UBT had the same detectable rate compared to the other two methods which were usually used clinically, but it was simple,rapid and safe,and was worth spreading clinically.